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F G Benavides

Publications and source records attributed to F G Benavides.

40 records · Page 3Linked to original sources

[Validation of a questionnaire for retrospectively measuring occupational pesticide exposure].

OBJECTIVE: The aim of this study is to validate a questionnaire intended to assess retrospective occupational exposure to pesticides in a case control study of workers exposed to pesticides and congenital malformations. METHODS: Occupational data were gathered through personal interviews to 56 agricultural workers and this information was compared to: 1) personal interviews with the workers' foremen, 2) direct observation of working places and 3) another questionnaire self-administered previously by the workers as a part of the "Training Program for Pesticide Applicators". RESULTS: Accuracy and reliability indices are high for variables such as the crops where the interviewees have been working, the time period of the treatments with pesticides and the use of personal protection during treatments (sensitivity ranges between 0.81 and 1 and Kappa index ranges between 0.65 and 0.80). However, for variables such as the duration of the treatments and the pesticides used, sensitivity values range between 0.32 and 0.50. CONCLUSIONS: The results suggest that the questionnaire is a valid tool for measuring some items but in order to improve the quality of the exposure assessment the questionnaire was modified, including a question about size of treated areas (as a proxy variable for duration of treatments) and prompt lists were developed to make easier recall by the workers of specific pesticides used in treatments.

Abnormalities, Drug-Induced↗

[Minimum basic set of data of hospital discharges as a source of information for a study of congenital abnormalities].

BACKGROUND: The purpose of this study is that of assessing the validity of the computerized diagnoses of hospital discharges of congenital defects by comparing them with the information included in the medical history. METHODS: Based on the discharge records generated over a one-year period at 7 hospitals in the Autonomous Region of Valencia, 100 children were selected at random from each hospital. As a standard, the diagnoses stated in the medical histories were indexed and coded. Solely those discharges having taken place during the first year of life were considered. A study was also made of the type, seriousness and individual or combinations of congenital defects. A calculation was made of the sensitivity, specificity, predictive values and the 95% confidence intervals thereof by the exact binomial method for the case studies (children) and the positive predictive value and sensitivity for the study of diagnoses. RESULTS: 126 children were detected as having congenital defects, and 201 diagnoses in medical records, and 83 children with congenital defects and 108 diagnoses on record. For the detection of cases, the records showed a 64% sensitivity, a 99.1% specificity and some positive and negative predictive values of over 90%. With regard to the detection of diagnoses, the sensitivity was 46% and the positive predictive value 83%. The sensitivity varied a great deal depending upon the diagnoses. CONCLUSIONS: The hospital discharge records revealed a high degree of specificity and high predictive values, but a low degree of sensitivity. These facts must be considered when these records are used as a source of cases for the epidemiological studies of congenital defects.

Age Factors↗