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Biomedical subjects

F Gómez Castresana

Publications and source records attributed to F Gómez Castresana.

6 recordsLinked to original sources

The caudal gluteal vessels: a suitable recipient bundle for free bone grafting in the canine femur.

The caudal gluteal vascular bundle was analyzed in the dog to determine its suitability as a recipient area for free vascularized bone grafts in the femur. The anatomy of the caudal gluteal artery and vein, as well as the arterial blood flow, were studied. This bundle was also used to revascularize 50 free vascularized rib grafts for proximal and femoral shaft reconstruction. The pedicle was constant, long (6.12 +/- 1.85 cm), and easily accessible via a lateral approach. It was large enough (artery: 1.74 +/- 0.46 mm, vein: 2.27 +/- 0.69 mm) and had an adequate blood flow (99 +/- 8 ml/mn) for microvascular techniques. Due to the existence of three anastomotic vascular rings with both the superficial and deep femoral bundles, these vessels had a bidirectional blood flow. In all the free vascularized rib grafts the caudal gluteal vessels were distally based (reversed blood flow) and provided a sufficient blood supply to the grafted bone. These results suggest that the caudal gluteal vessels are excellent recipient vessels for research in the field of free vascularized bone grafts using the canine femur.

Animals↗

Revascularization of femoral head ischemic necrosis with vascularized bone graft: a CT scan experimental study.

An ischemic necrosis of the femoral head was induced in 15 mongrel adult dogs using the technique described by Gartsman et al. [10]. Five weeks later, a free vascularized rib graft was transferred into the previously induced ischemic femoral head. High resolution computed tomographic scanning was used to evaluate revascularization 4, 8 and 12 weeks after grafting. The femoral head exhibited new vessel formation throughout the study. Arterial terminal branches arising from the rib graft medullary and periosteal circulations extended beyond the rib graft, entered the head, and reached the subchondral plate. Even where the rib graft did not replenish the central core of the head, there was vascular supply from the grafted bone's vascular tree. These results suggest that a free vascularized bone graft is able to revascularize an experimentally induced ischemic femoral head necrosis.

Animals↗

Role of free vascularized bone grafts in the experimentally-induced ischemic necrosis of the femoral head.

In 15 mongrel adult dogs, an ischemic necrosis of the femoral head was produced, following the technique described by Gartsman and colleagues. Five weeks later, a 6- to 8-cm long rib graft was harvested with its vascular bundle and transferred into the previously induced ischemic femoral head. Microsurgical anastomoses were performed for revascularizing the rib graft. Dogs were studied using scintigraphy, blood flow measurements, roentgenograms, angiograms, and histology at four, eight and 12 weeks after grafting. New bone and vascular formation was exhibited throughout the study, as demonstrated by a highly positive scintigraphic activity and the formation of numerous arterial terminal branches arising from the rib graft circulation which entered the femoral head and reached the subchondral plate. The formerly necrotic femoral head bone exhibited osteoblastic activity, viable osteocytes, and well-populated bone marrow. The rib graft was also incorporated into the femoral head. These results suggest that a vascularized bone graft is able to repair a femoral head necrosis, and may be considered a rational approach for clinical purposes.

Anastomosis, Surgical↗

Vascular medullary patency in free vascularized bone grafts: CT scan experimental study.

In an experimental study using 13 mongrel adult dogs, 6 cm of the anterior part of the left ninth rib were harvested, including the posterior intercostal vessels. The grafts were transferred, based on the periosteal circulation alone, to a previously induced femoral head ischemic necrosis. Microsurgical anastomoses were performed between the posterior intercostal vascular bundle and the caudal gluteal vessels at the recipient thigh zone. Using a high resolution CT scan and morphologic evaluation, it was demonstrated that the medullary circulation network filled on contrast medium. The entire cortex and medullary cavity were supplied from endosteal vessels coming from a reversed periosteal blood flow.

Anastomosis, Surgical↗