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F Gürgen

Publications and source records attributed to F Gürgen.

3 recordsLinked to original sources
PubMed1986

Modulation of spinal motor asymmetry by neuroleptic medication of schizophrenia patients.

The effects of chlorpromazine treatment on spinal motor asymmetry was studied in right-handed chronic schizophrenia patients. Spinal motor asymmetry and lower motor neuron excitability were tested by the Hoffmann reflex recovery curve. In drug-free patients, the Hoffmann reflex recovery curve from the left leg was significantly higher than that from the right leg as in the healthy subjects. This spinal motor asymmetry disappeared and even reversed within three weeks of the neuroleptic treatment. The chlorpromazine medication lowered the left recovery curve predominantly, and slightly augmented the right recovery curve. These results do not support the hypothesis that schizophrenia may be related to an overactive, and yet functionally deficient, dominant hemisphere. It was concluded that the cooperative function of both cerebral hemispheres should be taken into consideration to explain the neural mechanisms of schizophrenia.

Adult↗
PubMedDate not supplied

Neural-network-based decision making in diagnostic applications.

In this article the NN approach for medical decision making was applied for three specific examples. The first example was decision making with single-valued data for IUGR detection. The second example was decision making with double-valued data in prediction of ovulation. The third example was the use of independent NN modules and consensus theory for prediction of ovulation time. The NN approach has superiority over classical statistical approaches for decision making with medical data for the following reasons: 1. It is distribution-free. 2. It captures correlative features and does not need any specific consideration for mutual test dependence. 3. It provides weighted reliability of various tests. 4. It produces fast, accurate results. The statistical decision approach will probably outperform the NN approach in making decisions when an accurate distribution model is provided. However, the NN is proposed as a useful tool to help physicians in decision making and diagnosis of certain symptoms. The capability and performance of this tool has generally been proven in combining mutually dependent medical tests.

Algorithms↗