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Biomedical subjects

F Galve Royo

Publications and source records attributed to F Galve Royo.

7 recordsLinked to original sources

[Distant metastases in patients with advance laryngeal carcinoma].

Patients with advanced stage cancer larynx have a higher risk of development of distant metastases which means a bad prognosis. In our study we try to identify risk factors with the idea of involve to all of these patients in more aggressive systemic therapy protocols. Data of 57 patients surgically treated, with squamous pharyngolaryngeal carcinoma, stage III and IV, are evaluated. Advanced T stage or more extensive neck disease more often caused distant metastases (p < 0.05), and also the histological evidence of tumor invasion in three or more cervical nodes (p = 0.02), and poorly differentiated tumors (p < 0.05). Tumor site, surface area in cm, presence of ulceration, and loco-regional uncontrol were not associated with distant metastases.

Adult↗

[Passive smoking and other risk factors associated to the lower respiratory illnesses in sucking infants].

OBJECTIVES: We try to evaluate the frequency of lower respiratory illnesses (LRIs), during the first year of life and it's relation to other risk factors, overall passive smoking and modes of feeding. DESIGN: This is a retrospective study in our city. SETTING: Primary Health Care. PATIENTS AND OTHER PARTICIPANTS: The study population is 240 children during the first year of life, born in 1993 and we have collected clinical information about risk factors and LRIs number. MEASUREMENTS AND MAIN RESULTS: A 37% have suffered from at least one episode of LRIs, during the first year of life. The parental smoking appears in 46.6%. The incidence of LRIs was strongly associated with passive smoking (OR = 1.86), exclusive breast-feeding and at least for 5 months (OR = 2.1) and older brothers (OR = 3.12). The number of episodes of LRIs was statistically significative higher in males (males 0.82 +/- 1.67 episodes; females 0.48 +/- 0.67 episodes) (p = 0.0489). CONCLUSIONS: In our report, the risk factors more strongly related with LRIs in suckling infants are passive smoking, older brothers, male sex and less than 5 months of breast feeding.

Breast Feeding↗

[Acute otitis media in the first year of life and its relationship with various risk factors].

OBJECTIVE: The purpose of the present study was to evaluate the frequency of acute otitis media (OMA) in our city (urban population) during the first year of life and its relationship to some risk factors. PATIENTS AND METHODS: This is a retrospective study of 240 children. We collected information about risk factors (sex, gestational age, birthweight, duration of breastfeeding, older siblings, parental smoking and nursery care). We related these to the number of OMA episodes during the first year of life. RESULTS: Of the infants studied 40% had suffered at least one episode of OMA during the first year of life. There was a higher incidence during winter and spring. Three out of every four episodes occurred after six months of age. The incidence of OMA was strongly associated to whether there were older siblings (odds ratio: 1.98) and to the male sex (odds ratio: 1.98). Children in the breastfed group (exclusive breastfeeding for at least 5 months) have less otitis episodes than the milk-adapted formula group, but the difference was not statistically different (0.41 +/- 0.68 vs 0.69 +/- 1.01 episodes; p = 0.11). CONCLUSIONS: In our report, the only risk factor strongly related with OMA in suckling infants are the presence of older siblings and the male sex. Breastfeeding did not have a protective effect in comparison to commercial formula, although a prospective study might be of interest for further addressing this issue.

Acute Disease↗

[Medicosocial profile of the crucial caregiver. Is he/she an occult patient?].

OBJECTIVE: To determine the prevalence of physical pathology (morbidity felt) and psychological unease (anxiety-depression) in crucial carers for disabled patients, and so establish a profile of them. DESIGN: An observational study. Analysis of two historical cohorts. SETTING: Primary care. Urban health centre. PATIENTS: The exposed cohort was made up of 54 carers for disabled patients, chosen at random from the records at our Centre. The non-exposed cohort (n = 54), matched for age, gender and educational level, was chosen at random from the consulting rooms. MEASUREMENTS AND MAIN RESULTS: By means of a questionnaire, descriptive variables were collected, i.e. the morbidity felt, consumption of medicine, psychological unease (Goldberg's anxiety-depression scale), perception of social support (modified Duke Unl), index of the effort of the carer (IEC) and the profile of the person being cared for. The "typical" carer was a 57-year old woman (CI 95: 54-61), with a low educational level, daughter or wife of the disabled person, who received external help in few cases (11%). Problems of health referred to by carers (Arthralgia, migraines, asthenia, feeling depressed and insomnia), are more frequent (p < 0.001) than in non-carers. 75% took some medication, as against 45% of non-carers (p < 0.001). 83% displayed anxiety and 63% depression, against 36 and 37%, respectively, in the non-exposed cohort. A high IEC implied greater risk of anxiety (p < 0.05) and depression (p < 0.001). CONCLUSIONS: The crucial carer has a greater prevalence of physical and psychological morbidity. A high IEC and a perception of low social support create the conditions for higher anxiety and depression. Caring for the carer needs to be integrated into care for the disabled patient.

Aged↗

[Is general screening for anemia and iron deficiency justified in nursing infants?].

OBJECTIVE: To establish the necessity of anemia and iron deficiency screening in breast-feeders in our environment. DESIGN: A crossover study, after data collection from case records. SETTING AND PATIENTS: 93 children of 18 and 24 months living in a urban area. All of them are included in the Healthy Breast-feeder Programme of the Health Center of Teruel city. INTERVENTIONS: Detection in venous blood of hematocrit, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, transferrin saturation and ferritin in serum. MEASUREMENTS AND MAIN RESULTS: We founded a 1.1% of anemia with iron deficiency and a 3.4% of latent iron deficiency. We detected a total of 5.4% cases of iron deficiency. We didn't find any statistical significance when comparing the haematic values among children who had received different kinds of milk nor in relation with the time in which they got it. We didn't find either any differences when comparing such values among those who had received iron prophylaxis and those in which this treatment was not considered necessary. CONCLUSIONS: Therefore we suggest selective iron prophylaxis for risk groups and laboratory studies only in those with evident signs of anemia or iron deficiency.

Age Factors↗