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Biomedical subjects

F García López

Publications and source records attributed to F García López.

At least 19 recordsLinked to original sources
PubMed2004

[Gastric uptake of gallium67 in the human immunodeficiency virus infection].

Nowadays, the human immunodeficiency virus infection (HIV) is a chronic disease. In the frequent clinical situations with fever, lymph nodes and loss weight it is necessary to determine their etiology, for establishing a specific treatment. Gastrointestinal opportunistic infections or gastric lymphomatous or sarcomatous process, which can accumulate Ga67, may be present in the patient with acquired immunodeficiency syndrome. We report 2 cases with gastric uptake in which endoscopy and biopsy was obtained. In the first one, with previous treatment with omeprazol and almalgate for gastroesophagic reflux, endoscopy and biopsy were normal and in the second patient an Helicobacter pylori infection was diagnosed. We think that gastric uptake of Ga67 in HIV patients, must indicate to the clinician to rule out associated pathologies.

AIDS-Related Opportunistic Infections↗
PubMed2000

[Long course metastasis in renal adenocarcinoma. Adrenal gland involvement].

OBJECTIVES: To report two cases of metachronic adrenal metastasis (one contralateral and the other bilateral) from renal cell carcinoma with long survival. METHODS: Two patients with clear cell renal carcinoma that developed metastasis to the adrenals are described. Each patient had undergone three operations for solitary metastasis during the 8-years follow-up. The indications for the surgical management of solitary metastasis, morbidity, prognosis and recent investigational treatment possibilities reported in the literature are analyzed. RESULTS: Resection of the renal cell carcinoma achieved a survival of more than 8 years with a good quality of life and no significant surgical complications. The outcome, however, is poor. CONCLUSIONS: Although there was no lymph node involvement and the tumor was localized to the renal parenchyma, one patient developed solitary lung metastasis and contralateral adrenal metastasis 4 and 8 years after the initial diagnosis, respectively. In the other case, contralateral adrenal metastasis appeared three years later. The possibility of long-term metastasis to the adrenal gland should be taken into account due to renal vein involvement. Preservation of the adrenal gland at the initial surgery (lower pole tumor) led to adrenal metastasis 8 years after the initial diagnosis. The prognosis is poor in both cases and the situation is discouraging for the urologist.

Adenocarcinoma↗
PubMed2000

[Hearing loss and human immunodeficiency virus infection. Study of 30 patients].

OBJECTIVE: To asses hearing loss in patients infected with the human immunodeficiency virus (HIV) and its relationship with clinical stage (fulfillment of diagnostic criteria for human acquired immunodeficiency syndrome/AIDS) and degree of lymphocyte depletion (number of CD4+ lymphocytes). METHODS: Assessment of thirty consecutive HIV-infected patients regarding the presence of subjective hearing loss, pure-tone audiometry, brain stem auditory evoked potentials (BAEP); and number of CD4+ lymphocytes and treatment with antiretroviral drugs. RESULTS: Forty percent of patients reported hearing loss; 33% had an abnormal audiometry and BAEPs were abnormal in 56% of patients. The most common findings included high-frequency sensorineural loss and an increase in the wave III latency and interaural I-V difference. Subjective hearing loss and an abnormal audiometry were both related to the administration of antiretroviral drugs, whereas abnormal BAEPs were related to AIDS and low CD4+ lymphocyte counts. CONCLUSIONS: In HIV infected patients, an abnormal BAEP is the most common audiologic disorder, particularly in the advanced stages of the disease.

Adult↗
PubMed2000

[Evaluation of the risk of osteoporosis in postmenopausal patients in the Hospital Luis Castelazo Ayala of the Mexican Social Security Institute, using a risk factor questionnaire].

Osteoporosis has a great impact on the population due to economic and health implications. For these reasons there is great interest to find the best prevention, diagnosis and treatment criteria. Postmenopausal women are at increased risk due to estrogen deficiency that is present in this stage of life. Through an oral interview the risk of osteoporosis in postmenopausal women was evaluated. The questionnaire was applied to 150 postmenopausal patients, questioning age, ethnic group, history of rheumatoid arthritis, use of estrogenic replacement therapy and body weight. Osteoporosis risk considered when a punctuation of 6 or greater. It was found that 85 of the patients had a punctuation of 6 or greater, with a mean punctuation of 7.5, indicating the risk of osteoporosis in our population. The most important factors that increased the punctuation and the risk to present osteoporosis were body weight and the lack of estrogen replacement therapy. We consider that these kind of questionnaires may be useful to detect the population at risk for osteoporosis and in base to this the adequate exams for diagnosis must be ordered.

Body Weight↗
PubMed1999

[Gammagraphy of somatostatin receptors in an ACTH secreting thymic carcinoid].

Ectopic ACTH secretion represent 10 to 15% in the causes of Cushing's syndrome. Carcinoid tumor of the thymus is a rare neoplasm and is currently believed to arise from population of thymic cells of neural crest origin. We present the case of a 43-year-old man with a corticotropin hormone (ACTH) secreting thymus carcinoid. 111In-octreotide scintigraphy demonstrated an intense uptaken on the lesion. The surgical specimen measured 17 x 18 x 18 cm and weighed 1. 25 kg. Postoperatively the patient was treated by chemotherapy and radiotherapy. A follow-up 111In-octreotide scintigraphy was normal. Very few scintigraphic images of these lesions have been published in the literature. Somatostatin receptor scintigraphy can be successful in the detection and follow-up of ACTH-secreting neuroendocrine tumors.

Adrenocorticotropic Hormone↗