Biomedical subjects
Publications and source records attributed to F Gascón Luna.
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Homozygous familiar hypercholesterolemia (FH) is a serious inherited disease caused by a genetic defect in the cell surface receptor that controls the degradation of low density lipoprotein (LDL). These patients often have myocardial infarction in their teens or early adulthood and are usually unresponsive to drugs. Recently it has been reported promising results using combined drugs regimens in patients with residual receptor activity. We report a new additional patient with receptor-defective homozygous FH treated with a combination of lovastatin and cholestyramine. The cholesterol levels were reduced in a 67% and there were adverse events related to treatment during a 7 month period of follow-up.
The authors depict one case of primary tuberculosis of the tonsil, they point out about its existence actually and they propose a protocol of early diagnosis.
The authors make a comparative study of the conventional culture media and a commercially available coagglutination test for detection of streptococcus beta-haemolyticus. They draw attention to the simplicity and quickness of the coagglutination test and to their high value of prediction.