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Biomedical subjects

F Geoghegan

Publications and source records attributed to F Geoghegan.

5 recordsLinked to original sources
PubMed2004

First observation of herpes-like virus particles in northern pike, Esox lucius L., associated with bluespot-like disease in Ireland.

Circular whitish granular lesions, 5-12 mm in diameter, were observed on the skin and fins of a wild northern pike, Esox lucius, caught in a lake in the Republic of Ireland. Histological examination of the lesions revealed hypertrophied cells in the epidermis with deeply basophilic enlarged nuclei and dark-staining granular material in the cytoplasm. Transmission electron microscopy of these cells revealed naked hexagonal herpes-like virus nucleocapsids (97 +/- 7 nm) in their nuclei while the cytoplasm contained multiple aggregates of enveloped viral particles. This is the first report of herpes-like virus particles in northern pike originating outside North America, where esocid herpesvirus-1 (EsHV-1) has previously been reported. Shared clinical, histological, morphological and epidemiological findings suggest that the observed particles in this report may also be EsHV-1.

Animals↗
PubMed1985

Amniotic fluid infection with intact membranes in relation to stillborns.

The role of transamniotic fetal infection in the presence of intact membranes has attracted widespread attention. The present study is a reexamination of the autopsy material from 145 cases of macerated stillbirth observed in the National Maternity Hospital from 1979 to 1982. The objective was to ascertain the incidence of congenital pneumonia. No more than five cases were discovered, and in only two of these was there convincing evidence that the membranes were intact. The amniotic fluid infection syndrome seemed to be of little importance in the causation of late intrauterine death.

Amniotic Fluid↗
PubMed1983

Disseminated arterial calcification associated with acardius acephalus.

Widespread arterial calcification was shown at necropsy in an infant who died at age 5 days and whose twin was acardiac. The changes resembled closely those described in idiopathic arterial calcification of infancy and the possible importance of haemodynamic factors in the production of these changes is discussed.

Abnormalities, Multiple↗
PubMed1981

Traumatic intracranial haemorrhage in firstborn infants and delivery with obstetric forceps.

Exclusive of breech presentation, traumatic intracranial haemorrhage was demonstrated at necropsy on 27 occasions in 36 420 consecutive firstborn infants. All 27 were forceps deliveries. The main conclusion is that serious injury to the forecoming head at birth is almost invariably a direct effect of forceps. The relevance of this conclusion to some aspects of contemporary obstetric practice is discussed briefly.

Birth Weight↗