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Biomedical subjects

F Gordts

Publications and source records attributed to F Gordts.

At least 19 recordsLinked to original sources
PubMed2005

Consensus report on acoustic rhinometry and rhinomanometry.

With respect to acoustic rhinometry, new elements concern the problems related to the interpretation of the minimal cross-sectional area, and the presentation of a protocol for a multinational study, which aims to define a normal nose. Also, the previously issued recommendations for standardisation for technical specifications and standard operating procedures are briefly reviewed. For rhinomanometry, new insights into the field of fluid dynamics are highlighted, as well as their repercussion on more recent graphical representations for active anterior rhinomanometry such as four phases rhinomanometry and resistometry. For acoustic rhinometry as well as rhinomanometry, a more stringent standardisation of decongestive procedures is suggested.

Humans↗
PubMed2004

[Atypical Cogan's syndrome. Based on a case].

Cogan's syndrome is a systemic inflammatory disease that associates typical (interstitial keratitis) and atypical (such as anterior uveitis) ocular manifestations to vestibulo-auditory dysfunction. It has also a systemic vascular association of vasculitis type. We report a case of a 64 years old woman who presented an atypical form with anterior uveitis.

Female↗
PubMed2003

Gradenigo syndrome: a case-report.

We report a case of sixth nerve palsy as a rare complication of acute otitis media (apical petrositis). The clinical triad of acute otitis media, pain in the distribution of the fifth cranial nerve and sixth nerve palsy is known as Gradenigo syndrome.

Abducens Nerve Diseases↗
PubMed2002

Orbital involvement in sinus pathology: often without ocular pain.

Many and diverse sinus pathologies can present with an orbital involvement. Contrary to popular belief, uncomplicated rhinosinusitis causes rarely orbital pain or headaches. However, especially in children, acute ethmoidal rhinosinusitis can be complicated by an extension of the infection into the orbit. Also, isolated sphenoid sinusitis is often associated with significant ophthalmologic or neurological complications. Sinus surgery is another possible source of orbital complications associated with pain. The occurrence of orbital pain in these and other sinus pathologies is discussed, since early recognition and prompt therapeutic action are often necessary in order to avoid devastating sequellae.

Acute Disease↗
PubMed2000

Reference data for DPOAE in healthy newborns.

Distortion Product Otoacoustic Emissions (DPOAE) can be used as an alternative to Transient Evoked Otoacoustic Emissions (TEOAE). This study aims to establish normal values for DPOAE in healthy newborns. DPOAE were determined with the Madsen Celesta 503 at 0.5, 1, 2, 4 and 8 kHz with an unequal stimulus level of the primaries (L1 = 65 dB SPL, L2 = 50 dB SPL). DPOAE were present in 92.4% of the ears of the 185 babies tested at 4 days after birth. The 5% quantile and the median of the DPOAE of the right and left ears were calculated for the five frequencies tested. At 4 kHz there was a significant sex effect (mean amplitude of DPOAE was higher in female than in male babies) and at 2 kHz a significant interaction effect was found between sex and side. The calculated reference limits are open to comparison with data obtained using other commercial equipment.

Acoustic Stimulation↗
PubMed2000

Microbiology of the middle meatus: a comparison between normal adults and children.

Middle meatal samples were obtained from 52 carefully selected healthy adults. In 75 per cent of the test subjects bacterial organisms were cultured. However, growth was often poor and the predominant species suggest a commensal flora: coagulase-negative staphylococci were retrieved from 35 per cent, Corynebacterium sp. from 23 per cent and Staphyloccus aureus from eight per cent of the adults. These data are very different from those previously obtained among children where--even in the absence of obvious ENT pathology--the most frequently cultured organisms were typical sinusitis pathogens: Haemophilus influenzae present in 40 per cent, Moraxella catarrhalis in 34 per cent and Streptococcus pneumoniae in 50 per cent of children. Furthermore, Streptococcus viridans and Neisseria sp., both organisms that might be able to inhibit colonization by some of the pathogens and found commonly among children, are virtually absent in healthy adults.

Acute Disease↗
PubMed2000

Endoscopic endonasal surgery in choanal atresia.

Twenty-seven cases of choanal atresia operated between 1979 and 2000 have been reported from 4 different institutions (19 females, 8 males, age of first surgical procedure ranging from 2 days to 35 years). Of these 27 cases, 22 were previously untreated. The outcomes for 19 of these new cases were available for the present report. Bilateral atresias were somewhat more frequent (15 versus 12) and associated anomalies were present in 10 out of 27 patients. Details about the types of atresia, associated anomalies, surgical techniques, duration of stenting and outcomes are given together with a theoretical review on choanal atresia.

Adolescent↗
PubMed2000

Bacteriology in disease: failure of a micro-ecological balance?

Both aerobic (mainly alpha-haemolytic streptococci) and anaerobic micro-organisms (like Prevotella and Peptostreptococcus species) are able to interfere with the growth of potential pathogens such as group A beta-haemolytic streptococci, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. The present paper reviews the application of this concept of interference with respect to the development of common acute ear-, nose- and throat infections.

Acute Disease↗
PubMed1999

Management of rhinosinusitis in children.

The authors provide definitions for the different forms of pediatric rhinosinusitis, with an enumeration of the main symptoms and signs. They also provide the indications for CT scan examination and microbiological investigations. In addition, they emphasize the importance of concomitant systemic disease, such as allergy and immunological disorders. The adequate medical management, which is mandatory before any surgery, is considered and discussed, and the indications for surgery are provided.

Child↗
PubMed1999

Bacteriology of the middle meatus in children.

Little is known about the bacteriology of the middle meatus in children. Therefore, middle meatal samples were obtained from 50 children who underwent adenoidectomy or adenotonsillectomy, while a group of 50 children submitted to minor non-ENT surgical procedures, were used as a control group. Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae were the most frequent cultured organisms, not only in the ENT group (in 68, 50 and 60% of the children respectively) but also in the control group (40, 34 and 50%). These three potential pathogens were more frequently seen among the children of the ENT group but only for H. influenzae was the observed difference statistically significant (P = 0.009). On semiquantitative analysis, there seemed to be more negative cultures or cultures with only a few colonies in the control group, while the richer cultures were obtained from the ENT group. Again, only for H. influenzae, these differences reached a statistical significance (P = 0.003). Streptococcus viridans and Neisseria species, both organisms that might be able to inhibit colonisation by some of the pathogens, were more frequently cultured in the control than in the ENT group: Strep. viridans 30 vs. 10% (P = 0.025) and Neisseria species 14 vs. 2% (P = 0.069).

Child, Preschool↗
PubMed1999

Microbiology of the middle meatus in children requiring adenotonsillectomy.

Middle meatus samples were cultured in 120 children undergoing adenotonsillectomy with, or without, insertion of ventilation tubes. Every child (except one) had positive cultures. Haemophilus influenzae (62 per cent of the children), Moraxella catarrhalis (53 per cent) and Streptococcus pneumoniae (48 per cent) were the most commonly isolated bacteria. The presence of Moraxella catarrhalis and (to a lesser extent) Streptococcus pneumoniae was higher in younger children, while Haemophilus influenzae was cultured independently of age. Culture results of these middle meatal samples, carefully taken in order to avoid any contamination, probably reflect some ongoing sinus infection in these children requiring adenotonsillectomy. The problems inherent in the interpretation of surface cultures are addressed.

Adenoidectomy↗
PubMed1999

Distortion product oto-acoustic emissions as objective audiometry in a group of children with ventilation tubes.

The aim of this study was to evaluate distortion product oto-acoustic emissions (DPOAEs) as a means of objective audiometry in a population of children with ventilation tubes. We measured DPOAEs at two different stimulus levels--recorded transient evoked oto-acoustic emissions (TEOAEs) and obtained pure-tone audiometry (PTA). DPOAEs were compared with the normal range proposed by the Madsen company: the CELESTA 503 provides a 'normalized' distortion-product-gram which we compared with the pure-tone threshold of the test group. DPOAEs at 60 dBSPL were more easily obtained in the test group than TEOAEs and PTA. Correlation between 'normalized' DPOAEs and pure-tone thresholds was the strongest at 2 and 4 kHz. Surprisingly, DPOAEs at 60 dBSPL showed significant differences also at 2 and 4 kHz compared with the Madsen data. DPOAEs at 60 dBSPL might be an easy, objective test for evaluating auditory function and for determining hearing threshold at 2 and 4 kHz.

Acoustic Impedance Tests↗
PubMed1999

Neonatal screening for congenital cytomegalovirus infections.

We evaluated a screening program for the detection of congenital cytomegalovirus in 3075 unselected pregnant women. From each live-born child urine for CMV culture was collected within 7 days after birth. Each fetus expelled after a spontaneous second trimester abortion and each stillborn infant were also evaluated for a possible congenital CMV infection. For each congenital infection stored maternal sera were analysed to determine whether maternal infection was primary or recurrent. Fifteen out of the 3075 pregnancies studied resulted in a congenitally infected infant (0.49%). Nine maternal CMV infections were primary infections; five were recurrent infections, and in one case the type of infection could not be determined. Three congenital infections resulted in severe sequelae, leading to the termination of pregnancy in two instances and to neonatal death in one case. One of these severe fetal infections was due to a recurrent maternal infection. Follow-up of the other 12 neonates demonstrated hearing disorders in two children. One was born after a primary maternal infection and one after a recurrent maternal infection. We conclude that congenital CMV infections occurs in 0.49% of all pregnancies in the population studied. Twenty percent of the congenitally infected infants present severe sequelae at birth or during pregnancy, and an additional 17% have audiological deficits at 1 year of age. Severe sequelae may occur after both primary and recurrent maternal CMV infection.

Abortion, Spontaneous↗
PubMed1999

[Acquired enophthalmos associated with hypoplasia of the maxillary sinus and asymptomatic chronic maxillary sinusitis].

BACKGROUND: We report a case of progressive enophthalmos, maxillary sinus hypoplasia and radiological signs of sinusitis in a young woman. CASE REPORT: The patient had no history of sinus surgery or facial trauma. There were no signs of sinusitis. Functional endoscopic sinus surgery was proposed to restore the communication between the nose and the antrum. DISCUSS: The particular aspects of asymptomatic maxillary sinus and causes of maxillary sinus hypoplasia are discussed. We suggest that obstruction of the osteomeatal complex causes negative pressure in the maxillary sinus provoking bone alterations. These alterations cause the maxillary sinus hypoplasia and the enophthalmos.

Adult↗
PubMed1998

Management of rhinosinusitis in children: consensus meeting, Brussels, Belgium, September 13, 1996.

OBJECTIVES: To (1) provide definitions for the different forms of pediatric rhinosinusitis, with an enumeration of the main symptoms and signs; (2) provide indications for microbiological, allergic, and immunologic assessment as well as for imaging studies; (3) suggest standard medical management with judicious use of antimicrobial agents; and (4) discuss indications for surgery. DATA SOURCES: Clinical studies and literature data relevant to the different topics of pediatric rhinosinusitis. CONCLUSIONS: Rhinosinusitis in children is a multifactorial disease in which the importance of several predisposing factors changes with increasing age. Continued study to obtain a better understanding of the disease and carefully controlled comparative evaluations of medical and surgical therapies are suggested.

Child, Preschool↗
PubMed1998

Invasive sino-nasal aspergillosis: a case report.

A case of invasive sino-nasal aspergillosis in an immunocompromised child is reported. Prognosis of this fulminant disease is usually poor. This paper reviews the early symptoms, clinical manifestations, risk factors, diagnosis and treatment. Awareness of the disease and early diagnosis by histological examination is essential. Treatment should consist of early administration of i.v. Amphotericin B and extensive surgical debridement.

Anemia, Aplastic↗
PubMed1997

Unusual choanal polyps.

Four children with choanal polyps are presented. Their age and/or the site of origin of the polyps are unusual. At the time of diagnosis, the two boys were respectively 3 years 9 months and 4 years 6 months. The two girls were aged 9 and 10. In one of the patients the polyp originated from the sphenoidal sinus, in another from the inferior turbinate. The age of the child complicates diagnosis, endoscopic sinus surgery and postoperative care.

Child↗