Infections in the seronegative spondyloarthropathies.
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Biomedical subjects
Publications and source records attributed to F Gutierrez.
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We have developed a new method of computer image processing that allows true three-dimensional (3-D) images of the heart and great vessels to be reconstructed from standard ECG-gated two-dimensional magnetic resonance (MR) images. Contiguous 5-mm thick MR images of the thorax from the level of the cardiac apex to the aortic arch were obtained in 4 normal volunteers and 3 patients with congenital heart disease: 1 with pseudotruncus arteriosus and 1 with a ventricular septal defect, each with Eisenmenger's complex, and 1 with aortic coarctation. Each image could be obtained at up to seven different intervals throughout the cardiac cycle with ECG gating. The scanning procedure is noninvasive and requires no contrast material. Using standard software, images from each interval in the cardiac cycle were edited to isolate pertinent cardiac and great vessel structures. High-resolution 3-D reconstructions were formed for each interval by stacking the edited images. Sequential projection of 3-D reconstructions from each interval yields four-dimensional (includes time) cine views. Both 3-D and cine views can be obtained from any axis or divided in any plane to allow accurate, noninvasive assessment of cardiac and great vessel anatomy, chamber volumes, and regional and global wall motion. Noninvasive 3-D reconstruction of the heart and great vessels provides accurate anatomical data not available from standard cardiac catheterization or other noninvasive diagnostic procedures, and aids in the preoperative planning of the procedure to correct complex congenital malformations.
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Ocular cysticercosis is a rather infrequent entity even in developing countries. Several treatments have been proposed depending on the location of the organism within the eye. Three cases are described, emphasizing treatment of a subretinal cysticercus with sclerotomy instead of photocoagulation.
Magnetic resonance images have been obtained preoperatively in six patients with congenital heart disease. Contiguous sequences of electrocardiogram-triggered spin-echo images have been reconstructed in three-dimensional form to define the size and anatomic relationships to the great vessels and internal cardiac structures. Findings of magnetic resonance imaging were corroborated by angiographic and sector-scan echocardiographic studies and at operation. Individual scan slices were manually edited to separate the heart and great vessels from the blood within them and from extracardiac structures. Surface reconstruction software originally developed for craniofacial and orthopedic surgical planning was adapted for processing of cardiac magnetic resonance image sequences. Preoperative three-dimensional magnetic resonance imaging reconstructions were obtained in patients with aortic coarctation with ventricular septal defect, hypoplastic left ventricle, pulmonary artery atresia with ventricular septal defect, atrial septal defect, partial atrioventricular canal defect with anomalous pulmonary venous drainage, and tetralogy of Fallot with peripheral pulmonary artery stenosis. The reconstructions showed anatomic findings consistent with two-dimensional magnetic resonance imaging, echocardiography, cineangiography, and intraoperative findings. The three-dimensional images have a format that is familiar and consistent with the gross intraoperative appearance of the heart and great vessels. These three-dimensional images can facilitate the interpretation of magnetic resonance scan findings for cardiac surgeons without the sacrifice of significant clinical information.
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Ytterbium-DTPA was evaluated as a potential intravascular contrast agent. Ytterbium-DTPA was synthesized from ytterbium oxide and diethylene triamine penta-acetic acid (DTPA). CT scans of increasing concentrations of ytterbium and iodine showed that at 125 kVp, ytterbium was denser than an equal concentration of iodine. The LD50 of intravenous ytterbium-DTPA was 10 mM/kg (1.73 g ytterbium/kg) in rats. In enhanced CT scans and pulmonary angiography in dogs, ytterbium was visibly denser than iodine, and CT Hounsfield units showed greater enhancement of the aorta and inferior vena cava with ytterbium. The animals showed no sign of acute or delayed toxicity. Ytterbium-DTPA deserves further evaluation as a contrast agent for high kVp techniques.
The mediastinal vessels in 27 patients who had previously undergone vascular surgery were evaluated with use of magnetic resonance (MR) imaging for patency and the presence of stenosis. Thirty-six postoperative vessels or shunts were studied, including 11 aortas after coarctation or stenosis repair, 18 systemic-pulmonary shunts, four pulmonary artery or vein repairs, and three spiral vein grafts. Angiographic (n = 21), direct surgical (n = 1), contrast material-enhanced computed tomography (n = 1), or clinical (n = 13) findings were correlated with the MR findings. Overall, the accuracy of MR imaging for determination of patency was 100%. In patients with angiographic correlation and technically adequate MR examinations, MR imaging results were used to identify or exclude stenoses correctly in 66.7% of patent vessels. The four missed or underestimated stenoses occurred in vessels 10 mm or less in diameter.
Magnetic resonance imaging (MRI) was used for postoperative evaluation of spiral vein grafts in three patients with fibrosing mediastinitis who had undergone bypass of the superior vena cava (SVC) for SVC syndrome. The MRI images, obtained without ECG triggering, were compared retrospectively with postoperative bilateral arm venograms. Patent grafts were identified by MRI in all patients. Significant stenoses at innominate vein-spiral vein graft anastomoses in two patients were better demonstrated by venography than by MRI. MRI shows promise as a non-invasive technique for postoperative evaluation of spiral vein bypass grafts.
The authors report on experiences with fixateur extern according to Raoul Hoffmann in 110 open fractures of second-degree and third-degree severity. The patient material comprised 90 patients, of which a total of 71 (79 per cent) had polytraumas. It was shown that good results can be expected if fixateur extern is applied immediately. The advantages of good positioning and care of soft parts are emphasized. A detailed discussion is devoted to the specific problems of polytraumatized patients with second-degree and third-degree open fractures.
Four cases of benign cystic mesothelioma are described. The disease affects young white women (mean age, 30 years), and they present with chronic pelvic pain. At laparoscopy or laparotomy, multiple cysts ranging in size from 0.5 to 4 cm in diameter and containing clear fluid are seen. The disease commonly affects the pelvic organs and/or omentum. With the electron microscope, the cell of origin of this proliferative process is shown to be the mesothelial cell. The disease has been previously described under a variety of terms. There seems to be a tendency for recurrence, but no malignant potential is apparent. Treatment may be conservative with preservation of pelvic organs. Benign cystic mesothelioma should be considered in the differential diagnosis of cystic lesions of the female genital tract.
We sought to correlate esophageal symptoms with esophageal motility abnormality in 17 patients with mixed connective tissue disease (MCTD) and in 14 patients with systemic lupus erythematosus (SLE). Heartburn and regurgitation were common symptoms (11/17) in patients with MCTD, and most of the (10/11) exhibited significant manometric abnormalities. Additionally, impairment of esophageal peristalsis was found in four of the remaining asymptomatic patients. Severe esophageal aperistalsis was noted in nine MCTD patients. Patients with SLE also frequently reported esophageal symptoms (8/14), but significant motility abnormalities were seen in only three cases. In both patient groups good correlation between Raynaud's phenomenon and esophageal aperistalsis was found. Our results reveal that, although esophageal symptoms are commonly present in patients with both MCTD and SLE, severe esophageal motility abnormalities are more often found in patients with MCTD than in those with SLE.
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We have presented a case in which the fiberoptic laryngoscope was used for nasotracheal intubation, an alternative for the difficult laryngoscopy. We believe regional blocks combined with extensive topical anesthesia aid in the successful use of the fiberoptic laryngoscope for cases of difficult intubation in the practice of oral surgery. We were unable to obtain a complete sensory block with benzocaine or lidocaine spray since the mouth opening was less tha 1 mm. The bilateral superior laryngeal nerve block is a valuable adjunct to the procedure.
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