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Biomedical subjects

F H Boehm

Publications and source records attributed to F H Boehm.

At least 91 records · Page 5Linked to original sources
PubMed1979

Xerox telecopier transmission of fetal monitor tracings: a 4-year experience.

A telephone consultation system using the Xerox 400 Telecopier has been established to transmit fetal monitor data to a tertiary center from regional hospitals with limited experience in interpreting this data. This report reviews a 4-year experience with this consultative device, discusses both the advantages and disadvantages of such a program, and recommends the establishment of similar services in other tertiary centers. We believe that the establishment of such services can be of diagnostic and therapeutic benefit to inexperienced medical personnel when first confronted with the concept of fetal monitoring. Hopefully, by so doing, hospital use of fetal monitoring will increase.

Copying Processes↗
PubMed1977

Physostigmine's effect on diminished fetal heart rate variability caused by scopolamine, meperidine and propiomazine.

Physostigmine was given to 17 patients in labor, previously given scopolamine alone or meperidine and propiomazine in combination, to ascertain its effect on reversing the loss of fetal heart rate variability caused by the administration of these drugs. The results of the study indicated that scopolamine in doses of 0.65 to 1.08 milligrams diminished fetal heart rate variability in all 7 patients and physostigmine reversed this loss of fetal heart rate variability in all 7 patients within 4 to 17 minutes after injection of the first dose of physostigmine. Similar results were noted in 10 patients with the combination of meperidine, 50 mg, and propiomazine, 20 mg. It seems tenable from this study that physostigmine does cross the placental barrier and enters the fetal circulation and that this usually occurs within 3 to 17 minutes with an average of approximately 9 minutes. In the healthy fetus the loss of fetal heart rate variability caused by scopolamine, meperidine or propiomazine can be reversed by the use of physostigmine and this reversal seems abrupt and clinically measurable on the fetal monitor print out.

Adolescent↗
PubMed1977

Effects of nicotine and cocaine on the release of acetylcholine from isolated human placental villi.

According to our studies, human term placenta contains about 112 nmol/g of ACh. In the present studies, isolated placental villi were suspended in Kreb's bicarbonate buffer (pH 7.4) at 37 degrees and acetylcholine (ACh) released into the medium was analyzed by gas chromatography. The spontaneous release of ACh into the medium was linear with time and was 35 pmol/g/min. Cocaine in doses of 280 and 56o micrometer decreased the spontaneous release of ACh to 23, and 17 pmol/g/min, respectively. Raising the Ca2+ concentration in the Kreb's bicarbonate buffer from 2.34 to 4.64 mM, or the addition of nicotine (58 micrometer) to the bath increased the rate of release of ACh to 53 and 47 pmol/g/min, respectively. Cocaine decreased the rate of release of ACh even in the presence of Ca2+ or nicotine. ACh was not released when Ca2+ was absent in the medium. Nicotine did not stimulate the release of ACh in the Ca2+ free medium. High concentrations of K+ increased ACh release in the presence of Ca2+ and it did not have any effect on ACh release in the absence of Ca2+. These observations indicate that external Ca2+ is required for the release of ACh and cocaine acts possibly by preventing the entry of external Ca2+ into the syncytiotrophoblast, and thereby decreases ACh release from the placental villus.

Acetylcholine↗
PubMed1976

The oxytocin challenge test.

In a group of 152 high-risk pregnancies, 266 oxytocin challenge tests were reviewed. There were 137 patients with persistently negative oxytocin challenge tests with only one false-negative test being recorded. Fifteen patients who displayed a positive test at some time in their antepartum course are discussed along with other aspects of the oxytocin challenge test.

Adolescent↗
PubMed1976

Induction of labor with prostaglandin E2 administered orally.

The effectiveness of orally administered prostaglandin E2 in inducing labor was studied in 60 patients with uncomplicated, full-term pregnancies, using three dosage schedules. Although 40 patients did deliver, 11 patients' amniotic membranes ruptured at a time considered by the investigators to introduce an undesired variable in attempting to evaluate the drug. Twenty (33%) failed to deliver despite adequate Bishop scores. Side effects were noted in 45% of patients. No significant advantage for induction of labor occurred with the three dosage schedules used.

Adult↗
PubMed1975

Prolonged end stage fetal heart rate deceleration.

With the use of routine monitoring of all patients in labor, a number of confusing, seemingly ominous fetal heart rate tracings in otherwise normal, healthy patients have been observed. This report described one such type of pattern called prolonged end stage deceleration.

Female↗