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Biomedical subjects

F H Harvey

Publications and source records attributed to F H Harvey.

9 recordsLinked to original sources
PubMed1980

Brainstem abscess and the syndrome of acute tegmental encephalitis.

A 63-year-old man developed the acute onset and rapid progression of signs of lower brainstem dysfunction accompanied by a sterile cerebrospinal fluid containing moderate pleocytosis. Autopsy examination disclosed diffuse acute bacterial inflammation of the brainstem tegmentum. The findings in 55 additional cases of brainstem bacterial infections are reviewed and discussed with respect to differential diagnosis and potential treatment.

Brain Abscess↗
PubMed1980

"Typical" basal skull fracture of both petrous bones: an unreliable indicator of head impact site.

A basilar skull fracture that extends along both petrous bones is generally considered to be a response to impacts to the lateral aspects of the head. This generalization is not warranted as such a fracture often results from impacts to any point around the base of the skull or to the chin. These facts were appreciated as long ago as 1905 but present-day literature does not adequately reflect them. Eight carefully selected autopsy cases of fatal blunt head injury with well-documented single head impact sites and bilateral petrous bone fractures are presented. They illustrate the variety of impact sites that may produce bilateral petrous bone skull fractures.

Adolescent↗
PubMed1980

The significance of the amount of fluid surrounding the brain to the recognition of brain swelling (or atrophy) at autopsy: a new and routinely applicable method of diagnosing abnormal brain size.

A new method of measuring relative brain size (relative to the skull cavity) at autopsy is presented. It is convenient and accurate and may be applied almost routinely. It consists of measuring the volume of the brain and the fluids surrounding it. These two volumes together must equal the intracranial volume. An abbreviated method consists of relating the fluid volume to the brain weight. This abbreviated method should not be routinely relied on when the brain size deviates slightly from normal. A review of the pertinent literature shows that other existing methods of determining relative brain size are impractical. The significance of measuring peri-brain fluids at the time of brain removal has not been appreciated prior to this report.

Atrophy↗
PubMed1975

Traumatic production of an intracranial berry-like aneurysm in a monkey.

A berry-like dissecting intracranial aneurysm resulted from inadvertent puncture of the internal carotid artery during trans-palatal section of a monkey's optic nerve. The light and ultrastructural features are rather similar to those of human berry aneurysms supporting the notion that the latter are degenerative rather than congenital in origin.

Animals↗
PubMed1975

The large dense core vesicle: a normal organelle of the central nervous system myelinated axon.

Large dense core vesicles (LDCV) were found frequently enough in normal guinea pig central white matter, basis pontis and spinal cord posterior columns to be regarded as a normal organelle. A review of studies of LDCV and dense core particles (DCP), which have a different cytological localization and appear to be associated with a variety of diseases, suggests that they are the same, and hence remarkedly ubiquitous. LDCV should no longer be regarded as a type of synaptic vesicle, but as an incompetely defined organelle common to many cell types.

Animals↗