Methods of measuring biologically active enzyme dust in the environmental air of detergent factories.
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Biomedical subjects
Publications and source records attributed to F Hall.
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Detectability of abnormally high serum and urine amylases was investigated on patients with pancreatic diseases using amylase assays with substrates of different digestive rates to pancreatic amylase. Ratios of amylase activities determined by a chromogenic assay using a Remazolbrilliant Blue R starch (RBB assay) to those by Caraway's assay using a Lintner soluble starch (R/C ratio) were calculated on duodenal and salivary amylases obtained from 16 subjects undergoing a pancreozymin-secretin test. The R/C ratio of the duodenal amylase (M +/- SD = 0.56 +/- 0.12) was significantly higher (p less than 0.01 by F test) than that of the salivary amylase (M +/- SD = 0.36 +/- 0.10). Detectability of above-normal values of serum and urine amylases were compared with two assays in 77 pancreatic patients. The value for serum and urine amylases determined by the RBB and Caraway's assays exceeded the upper limit of normal in 37 and 58% by the RBB assay and 24 and 26% by Caraway's assay, respectively. Degrees of abnormality (ratio of the observed to the upper normal value) in serum and urine amylases were also significantly higher (p less than 0.05 for serum and p less than 0.01 upper for urine) by the RBB assay than by Caraway's assay. The RBB assay was more sensitive than Caraway's assay in detecting elevation of pancreatic amylase in serum and urine.
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A total of 3217 strains of coagulase-negative staphylococci and micrococci were tested for susceptibility to a collection of phages isolated from coagulase-negative cocci; it was concluded that a useful typing scheme could be developed. Of the strains of Baird-Parker's biotype 1, 72% were lysed by one or more phages, although rather a large proportion of strains are lysed by many phages to give a complex typing pattern.Normal persons commonly yield 10 or more distinguishable strains of coagulase-negative cocci in cultures from the nose and the skin.
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This study examined the progression of sleep-disordered breathing (SDB) over 1 year in two samples of elderly subjects: 45 healthy controls (20 men; 25 women mean age 74.8 years) and 27 recently spousally bereaved elders (9 men; 18 women, mean age 69.7 years). Although controls and bereaved subjects did not differ in the proportions with SDB, both groups showed a rise in the proportion of subjects with apnea hypopnea index > or = 5 and > or = 10 at 1-year follow-up and a small but statistically significant worsening in average maximum desaturation. The severity of SDB did not correlate with medical burden or with other clinical variables, such as severity of depressive symptoms. In summary, SDB increased longitudinally in both samples. This finding may have health implications for the aging population although at this time the implications are unclear.