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Biomedical subjects

F Handa

Publications and source records attributed to F Handa.

67 records · Page 4Linked to original sources
PubMed1981

A quantitative assay of porphyrins in leprosy patients. A spectrophotometric study.

Quantitative estimations of porphyrin in the blood, urine, and feces of 30 leprosy patients under treatment with dapsone, ten untreated cases, and 100 normal subjects were done by Rimington's method. Dapsone had no adverse effect on porphyrin metabolism because none of the cases of leprosy under study developed statistically significantly raised porphyrin levels in the blood, urine, and stools. Although erythrocyte coproporphyrin levels were significantly higher in leprosy patients than controls and urinary uroporphyrin levels significantly lower, most values fell within the normal range. These differences did not appear to have any clinical significance, and their cause remains unknown.

Coproporphyrins↗
PubMed1977

Cord blood porphyrins. A quantitative assay in newborn infants.

A quantitative assay of free erythrocyte porphyrins was done in umbilical cord blood of 30 newborn babies by a spectrophotometric method. The mean value of free erythrocyte protoporphyrin in umbilical cord blood was found to be 74.58 microng/100 ml packed erythrocytes and that of free erythrocyte coproporphyrin to be 0.77 microng/100 ml packed erythrocytes with a standard deviation of +/-29.99 and +/-1.48 respectively. Relationship between free erythrocyte protoporphyrin and free erythrocyte comproporphyrin and their correlations with birth weight and sex of the newborn baby were found to be statistically significant.

Birth Weight↗
PubMed1975

A case of variegate porphyria in an Indian.

A female patient aged 25 years developed abdominal and neurological symptoms followed by a photosensitive eruption during pregnancy. She was found to have variegate porphyria on investigation. Investigation of the family revealed on member having latent porphyria. To our knowledge, this is the first report of variegate porphytia from India.

Adult↗
PubMed1975

Incontinentia pigmenti et achromians.

A case is reported, apparently the first of its kind in the literature, of a female child in which there were not only pigmented lesions of incontinentia pigmenti but also hypopigmented lesions of incontinentia pigmenti achromians. The title incontinentia pigmenti et achromians is suggested for this combined disorder. The child also had associated lesions in the form of nail dystrophy, delayed dentition and epilepsy.

Child, Preschool↗