Biomedical subjects

F Hofbauer

Publications and source records attributed to F Hofbauer.

23 records · Page 2Linked to original sources

PubMed1978

[Permeability of the gastric mucosa for carcinogens in taurocholate-induced injury of the mucosa barrier].

The influence of taurocholate-induced damage of the gastric mucosal barrier on transmucosal movement of methyl-N-nitro-N-nitrosoguanidine (MNNG) was investigated on dogs with Heidenhain pouches. We also investigated whether or not MNNG influences the mucosal barrier. The results of 10 experiments revealed no effect of MNNG on the mucosal barrier, but a significant time-related decrease of intraluminal MNNG concentration in the presence of taurocholate.

Animals↗

PubMed1977

[Effect of calcitonin on various stress ulcer models in the rat].

The preventive effect of calcitonin (10 microgram/kg subcutaneously) on stress ulcer was examined in 135 rats. Three stress models were used: (1) immobilization, (2) immobilization and ketamine, (3) hypovolemia. Significantly lowered lesion rates under calcitonin were found in immobilization stress and hypovolemia models (14%, resp. 16%), compared with controls (78%, resp. 56%). Reduction of the severe lesions of the mucous membrane was the only significantly different result in the combination of immobilization and ketamine.

Animals↗

PubMed1976

[Fractures of the olecranon; late results (authors's transl)].

140 fractures of the olecranon were treated (69 conservatively, 71 surgically), of whom 71 were followed up (28 conservative, 43 operated fractures). The fractures are classified in 4 groups (A. transverse fractures, B. oblique fractures, C. comminuted fractures and D. fractures associated with other injuries in the elbow joint). Each of these groups is devided into 3 types according to the displacement of the fragments. Good results by conservative treatment were always seen in fractures with separation of the fragments less than 2 mm. A relative indication for surgical treatment is displacement from 2 up to 10 mm. Only surgical treatment can prevent non-union in fractures with separation of the fragments more than 10 mm. A new sheme for classification of the results is proposed, and late results of the followed up cases are reported. Immobilization of the elbow in full extension is rejected in the conservative treatment. The internal fixation of prestress type by the Weber technique and the osteosynthesis with Spongiosa-screw are the preponderant methods actually used in surgical treatment.

Adolescent↗

PubMed1976

[Mechanical ileus (author's transl)].

UNLABELLED: 181 patients with mechanical bowel obstruction were treated between 1965 and 1974 at the First Surgical Clinic of the University of Vienna. 172 were operated, 7 had conservative treatment. RESULTS: 1. the mortality was 24,3% and infavorably influenced by a) advanced malignant tumors, b) age over 60 years, c) preexistent peritonitis. -2. Enterotomy for bowel-decompression was in no case followed by a complication.- 3. Nobles operation should be performed only totally and in cases of severe adhaesions. 4. Discussion of the one stage operation in large bowel obstruction, which is only indicated in patients with good general condition. The high letality of 47% after operations in cases with ileus due to carcinosis peritonei requires critical indications for these operations.

Aged↗

PubMed1975

[Advances in the treatment of postoperative complications after abdominal operations. A comparative, retrospective analysis of two reported periods (author's transl)].

Period I (1958-64)included 227 complications, period II 257 complications. Altogether, 484 complications were evaluated in 436 cases. The by far higher lethality in period I (71,3 percent) compared to 41,1 per cent in period II can be explained by the lower frequency of relaparotomy of 24,6 percent (52,3 per cent in period II). The mortality after relaparotomy was almost equal in both periods. The central problem in the therapy of postoperative surgical complications can consequently be seen in the indications for relaparotomy. Therefore, to improve the results, a more active diagnosis and indication and adequate performance of the operation are necessary.

Abdomen↗