[The current problems in the development of Russian medical science. Interview by A. P. Lomakin].
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Biomedical subjects
Publications and source records attributed to F I Komarov.
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The schedule of estulic administration for stage I-II essential hypertension in more effective at lower doses and better tolerance when adjusted to circadian variations in arterial pressure. Six-month continuous estulic treatment results in regression of left ventricular myocardial hypertrophy.
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The studies have revealed that the type of gastric mucosa changes in the patients with duodenal ulcer correlates with the disease severity, and manifestations of the pathologic processes in the gastric mucosa depend on the stage of duodenal ulcer. The most grave changes in the gastric mucosa were revealed in the patients with hereditary predisposition to peptic ulcers. In contrast to normal subjects, gastric mucosa status in the patients with duodenal ulcer is liable to season-associated changes, these changes being the most manifest in spring and fall.
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The blood concentration of pituitary hormones (corticotropin, somatotropin, thyrotropin and prolactin) was studied in 145 male patients with aggravation of chronic pancreatitis and in 15 healthy male subjects. The pre-treatment concentration of corticotropin, somatotropin and thyrotropin was markedly increased and the level of prolactin had a tendency to decrease. By the end of treatment the level of thyrotropin and prolactin was fully normalized, the content of corticotropin had a tendency to decrease and the concentration of somatotropin somewhat decreased but did not reach the normal values. Changes in the blood level of pituitary hormones were more pronounced in the severe course of the disease and also when the level of pancreatic enzymes and hormones in the blood was high.