[Effects of solar activity on clinical pathology].
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Biomedical subjects
Publications and source records attributed to F I Komarov.
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The renal kallikrein system was studied in 62 patients with coronary heart disease complicated by Functional Classes (FC) I-IV circulatory insufficiency and in 18 apparently healthy individuals. The activity of the renal kallikrein-kinin system was found to decrease in parallel to increases in FC: insignificantly in FC I circulatory disorders and significantly in FG II-IV. The use of captopril in the acute drug test in the first days and after fortnight therapy caused increases in renal kallikrein-kinin activity in patients with FC II-IV circulatory insufficiency and its decreases in FC I. The heterogeneous pattern of time courses of changes in the activity of the renal kallikrein-kinin system appeared in the clinical picture of the disease as captopril-induced hemodynamic and morphofunctional changes in the heart of patients with different FC circulatory insufficiencies.
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The schedule of estulic administration for stage I-II essential hypertension in more effective at lower doses and better tolerance when adjusted to circadian variations in arterial pressure. Six-month continuous estulic treatment results in regression of left ventricular myocardial hypertrophy.
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The studies have revealed that the type of gastric mucosa changes in the patients with duodenal ulcer correlates with the disease severity, and manifestations of the pathologic processes in the gastric mucosa depend on the stage of duodenal ulcer. The most grave changes in the gastric mucosa were revealed in the patients with hereditary predisposition to peptic ulcers. In contrast to normal subjects, gastric mucosa status in the patients with duodenal ulcer is liable to season-associated changes, these changes being the most manifest in spring and fall.
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