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Biomedical subjects

F I Komarov

Publications and source records attributed to F I Komarov.

At least 55 records · Page 3Linked to original sources

[Improving drug therapy in circulatory insufficiency: the role of renal kallikrein-kinin system].

The renal kallikrein system was studied in 62 patients with coronary heart disease complicated by Functional Classes (FC) I-IV circulatory insufficiency and in 18 apparently healthy individuals. The activity of the renal kallikrein-kinin system was found to decrease in parallel to increases in FC: insignificantly in FC I circulatory disorders and significantly in FG II-IV. The use of captopril in the acute drug test in the first days and after fortnight therapy caused increases in renal kallikrein-kinin activity in patients with FC II-IV circulatory insufficiency and its decreases in FC I. The heterogeneous pattern of time courses of changes in the activity of the renal kallikrein-kinin system appeared in the clinical picture of the disease as captopril-induced hemodynamic and morphofunctional changes in the heart of patients with different FC circulatory insufficiencies.

Adult↗

[Status of gastric mucosa in duodenal ulcer at various stages of the disease in different seasons].

The studies have revealed that the type of gastric mucosa changes in the patients with duodenal ulcer correlates with the disease severity, and manifestations of the pathologic processes in the gastric mucosa depend on the stage of duodenal ulcer. The most grave changes in the gastric mucosa were revealed in the patients with hereditary predisposition to peptic ulcers. In contrast to normal subjects, gastric mucosa status in the patients with duodenal ulcer is liable to season-associated changes, these changes being the most manifest in spring and fall.

Adult↗