PubMed Health⌕ Search

Biomedical subjects

F I Komarov

Publications and source records attributed to F I Komarov.

At least 127 records · Page 7Linked to original sources

[Modern aspects of nitro preparation use].

On the basis of clinical examination and the results of bicycle ergometry and echocardiography in 58 patients with chronic ischemic heart disease the authors determined the contingent of patients in whom long-acting nitrates were most effective. The high clinical effectiveness of the agents in patients with symptoms of the initial stage of cardiac insufficiency is proved and the absence of any essential differences between long-acting nitrates in the character of their effect on hemodynamics is shown. It is established that nitroglycerin and long-acting nitrates cause a qualitatively similar effect on myocardial contractile function and intracardiac hemodynamics in patients with ischemic heart disease.

Adult↗

[Dynamics of the echocardiographic indices of myocardial contractile function in chronic ischemic heart disease under treatment with blockaders of the cardiac beta-adrenergic receptors].

The article discusses the results of dynamic echocardiographic examination of 46 patients with chronic ischemic heart disease before and after 15-day treatment with agents capable of blocking beta-receptors: propranolol (anaprilin), pindolol (visken), talinolol (cordan) which were prescribed in mean therapeutical doses. It is shown that agents blocking beta-adrenergic receptors lead to regular decrease in the indices of myocardial contractility. The character of changes in the volumetric characteristics of the left ventricle depends on the initial levels of arterial pressure and the degree of its dynamics during treatment with beta-adrenergic blocking agents. In patients with chronic ischemic heart disease developing against the background of hypertensive disease the dynamics of changes in the volumetric indices depends on the degree of arterial pressure reduction.

Adrenergic beta-Antagonists↗

[State of the myocardial contractile function of the right sections of the heart and of the pulmonary hemodynamics in liver cirrhosis (based on clinical instrumental and morphological study data)].

The state of pulmonary hemodynamics and the contractile function of the right parts of the heart were studied clinically and instrumentally in 35 patients with diffuse chronic pathological conditions of the liver. The lungs and heart were examined morphologically in 24 persons who had died from cirrhosis of the liver in the edematous-ascitic stage. Pulmonary hypertension was found to be directly dependent on the degree of the diffuse affection of the liver. Secondary-compensatory changes in the contractile function of the myocardium of the right parts of the heart in response to increase of pressure in the pulmonary artery in patients with cirrhosis of the liver were proved to occur.

Adult↗