[Current status of waiting time of ambulatory patients and its evaluation].
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Biomedical subjects
F Ihara
Publications and source records attributed to F Ihara.
Effect of diets containing different levels of calcium, phosphate, and vitamin D3 on tooth uptake of 47Ca-chloride in rat models: comparison with bone uptake.
The effect of dietary manipulation on global tooth uptake of 47Ca-chloride was evaluated in three rat models of metabolic bone diseases verified by histologic bone study. The 24-hr tooth uptake of 47Ca-chloride was significantly decreased in the osteomalacic group, and was increased in the osteoporotic group at the fourth week. Tooth uptake closely paralleled femoral uptake at a correlation coefficient of 0.73 (p less than 0.01). The uptake of 47Ca-chloride in tooth was found to be more affected by dietary manipulation than that in femur in our rat models.
Animals↗
Bone mineral density of the lumbar spine by dual photon absorptiometry: age-related regression in normal Japanese subjects and fracture threshold in osteoporotics.
The bone mineral density (BMD) of the lumbar spine was determined by DPA in 280 normal Japanese volunteers and 11 osteoporotic women with compression fractures. In women, bone loss started from the mid thirties and accelerated after the age of 50 years at the rate of 0.75% (0.0074 g/cm2) per year. In men, bone loss started from the mid twenties and occurred linearly at the rate of 0.30% (0.0032 g/cm2). The overall diminutions in vertebral BMD throughout life in men and women were 13.0% and 24.3%, respectively. The mean vertebral BMD of the osteoporotic women with recent compression fractures was 37.5% lower than that of age-matched controls. The 90th percentile for vertebral BMD in this group was 0.584 g/cm2. By the age of 80 years, approximately one-fifth of normal Japanese women have BMD values less than this.
Adult↗
Measurement of 24-hour whole-body retention of Tc-99mMDP with a thyroid uptake probe: quantitative assessment of metabolic and metastatic bone diseases.
A new method for the measurement of 24-hour whole-body retention (WBR) of Tc-99mMDP, using a thyroid uptake probe with a normal scintigraphic dose was established. Its clinical significance was evaluated in 106 subjects over 20 years old with various bone disorders, including metabolic and metastatic bone diseases. Reproducibility of 24-hour WBR in 10 patients was very good (y = x - 0.3, r = 0.996). The 24-hour WBR of Tc-99mMDP in healthy subjects was 30.4% +/- 4.6%. The WBR values for patients with chronic renal failure, metastatic bone disease, osteomalacia and hyperthyroidism were 98.4% +/- 3.0%, 44.0% +/- 8.0%, 50.7% +/- 2.8% and 39.4% +/- 6.5%, respectively, which were significantly higher when compared with the healthy group. However the WBR of the steroid-induced osteoporotic group was significantly lower (17.3% +/- 5.4%), suggesting the possibility of being able to differentiate osteoporotic patients from healthy subjects. For assessment of the value of 24-hour WBR, simultaneous bone imaging was essential so as to be able to exclude the effects of arthropathy and/or fracture, which were often found in the older age group.
Adult↗