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Biomedical subjects

F Imperadore

Publications and source records attributed to F Imperadore.

10 recordsLinked to original sources

[Heart arrest caused by ventricular fibrillation in acute biliary pancreatitis: a case report and etiopathogenetic hypothesis].

Acute pancreatitis and/or gallbladder disease precipitating angina pectoris, or producing arrhythmias or ST-T wave changes on electrocardiography in the absence of coronary artery disease, have frequently been mentioned. Many attempts have been made to explain the etiology of these findings. To the authors' knowledge, this report is the most dramatic expression of pathogenetic mechanisms which are still considered hypothetical.

Acute Disease↗

[Hemodynamic and coronary angiographic performance at a center with medium-low activity: organization model, activity indicators, and costs].

BACKGROUND: In order to evaluate the cost-effectiveness of coronary angiography performed in a low volume Center, we examined our 1-year activity. METHODS: The organizational model of the multipurpose cardiac catheterization laboratory is described. In this type of facility both coronary angiographic and electrophysiological studies are performed. To evaluate the laboratory performance we examined the utilization level, the appropriateness of the studies, the complication rates and the number of studies that had to be repeated because of inadequate data or image quality. The costs were calculated for the in-house laboratory setting (the actual scenario) and for the 25 km distant laboratory setting (the historical scenario). RESULTS: The laboratory caseload of coronary angiography was 342 studies, 46% of the overall laboratory activity; 175 patients (51%) underwent non-pharmacological therapy, 129 patients (38%) were treated with medical therapy; the percentage of patients with normal coronary arteries was 11%. Two patients (0.58%) had vascular complications, 1 patient (0.29%) developed an acute myocardial infarction 2 hours after coronary angiography without any evidence of angiographic modifications at the repeated study. In no patient the study had to be repeated because of inadequate data or image quality. The mean cost of a coronary angiography was Lit. 512,000 (265 Euro) for the actual scenario; it would have been Lit. 694,000 (359 Euro) for the historical scenario, with Lit. 182,000 (94 Euro) saved. CONCLUSIONS: These findings are consistent with the accepted criteria of good laboratory performance and cost-effectiveness. Thus coronary angiography can be performed effectively and efficiently in a low volume Center.

Cardiac Care Facilities↗

[Efficacy of treatment with rt-PA of massive pulmonary embolism in patients with contraindications for thrombolytic therapy].

Pulmonary embolism is a life-threatening condition that is accompanied by significant morbidity and mortality. In massive pulmonary embolism, where restoration of pulmonary arterial flow is urgently required, the only options available are surgical thromboembolectomy and/or thrombolytic therapy. Unfortunately, a large part of thromboembolic diseases is also considered as an absolute or relative contraindication to thrombolysis. The purpose of this paper was to emphasize the possibility of new thrombolytic agents of disregarding, according to circumstances, the contraindications to thrombolytic treatment.

Aged↗

[Myocardial infarct with ST segment depression: an absolute contraindication to thrombolytic therapy?].

The benefit of thrombolytic reperfusion has been demonstrated widely in patients who present with ST segment elevation and develop myocardial infarction. Instead, the role of thrombolytic therapy in patients who present with ST segment depression and develop myocardial infarction is still unresolved. The purpose of this paper is to review the literature on the subject and give rise to reconsideration of thrombolytic therapy in this subgroup of patients who are usually excluded from receiving thrombolytic agents because of the absence of indications and the presence of contraindications.

Angioplasty, Balloon, Coronary↗

[Clinicopathological conference: sudden coronary death in a 32-year old man].

A 32-year-old man without risk factors for coronary artery disease but moderate cigarette smoking died suddenly 5 years after a cardiological check-up for chest pain on effort. Autopsy investigation ruled out extracardiac causes of death and pointed to a multivessel coronary artery disease with organized and recanalized occlusive thrombosis, sometimes superimposed to smooth muscle cells proliferation, in the absence of peripheral vascular disease. Thromboangiitis obliterans of the coronary arteries or accelerated atherosclerosis complicated by thrombosis due to endothelial erosion are debated as possible etiopathogenetic mechanisms. The case is still open for achieving a final diagnosis.

Adult↗

[Intramural aortic hematoma].

Aortic dissection is a medical and/or surgical emergency that is usually catastrophic if not diagnosed and treated promptly. Transesophageal Doppler echography provides an accurate method of diagnosing and evaluating dissection of aortic aneurysm. Due to the high resolution of transesophageal echocardiography, special subtypes of aortic dissection such as intramural hemorrhage can be diagnosed. The purpose of this paper is to report a case and review the anatomical, clinical and transesophageal echocardiography aspects of aortic dissection without intimal rupture (intramural hematoma).

Aged↗

[Congenital arterio-venous coronary fistula associated with patent ductus arteriousus: description of a clinical case and review of the literature].

Congenital coronary artery fistulae are rare anomalies (0.27-0.4% of all congenital heart defects) and consist of a communication between a coronary artery and a cardiac chamber, a great artery or the superior vena cava. The association of these congenital anomalies with other congenital cardiovascular defects is unusual. The purpose of this paper is to report a case of congenital coronary fistula between the anterior descending coronary artery and the pulmonary artery associated with patent ductus arteriosus and to review the literature on the subject.

Adult↗

[Heart rupture at the right atrial level as the first manifestation of malignant lymphoma].

Primary heart lymphoma is an extremely rare condition and metastatic lymphomas constitute 9% of the total heart metastases. In most cases the lymphomatous involvement of the heart and/or pericardium is seen only at autopsy. It is unlikely that cardiac manifestations are the initial presentation of malignant lymphoma. We report a case of malignant lymphoma presenting with cardiac tamponade secondary to right atrial rupture.

Aged↗

[Dissection of the ascending aorta complicated by acute myocardial infarction in a patient with Marfan's syndrome and anomalous origin of the left circumflex artery. Description of a case].

Acute myocardial infarction is a rare complication of ascending aortic dissection; it is usually due to the coronary ostium involvement. The authors describe an unusual case with anomalous left coronary origin too; they suggest that, due to this combination, the aneurysmatic area pushes the anomalous coronary artery, causing acute myocardial infarction.

Adult↗