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Biomedical subjects

F Ioli

Publications and source records attributed to F Ioli.

22 records · Page 2Linked to original sources

[Functional recovery in pulmonary tuberculosis].

At first Authors explain the stages of tubercular disease in which a programme of functional respiratory rehabilitation can be advised. Then they deal with the main aspects of rehabilitating treatment in some tubercular manifestations, as sero-fibrinous pleural effusion, tubercular empyema, parenchymal fibrosis and surgical reliquates. With regard to surgical reliquates, we mostly consider pulmonary resections and pleural skinning. At last Authors recall the indications to physical exercise training, that are constituted by some reliquates of tubercular pathology, and they resume the accomplishment modalities of such a programme in order to allow every patient wide possibilities of social reintroduction.

Breathing Exercises↗

Sustained-release anhydrous theophylline in preventing exercise-induced asthma.

A number of drugs have been taken into consideration as to their efficacy in preventing exercise-induced asthma (EIA), which may be a reliable model for the investigation of bronchodilating agents. 15 asthmatic patients (mean age 21.1 +/- 10.7), EIA positive (free running test), were selected for a double-blind cross-over study of a sustained-release theophylline preparation against placebo. Patients underwent four subsequent bronchoprovocation tests by means of free running, at a 3-hours' interval, with a prior administration (3 h before the first test) of the drug at the dose of 7-8 mg/kg or the placebo. Lung function was tested (FEV1.0, FEF50, FEF25, sGaw) after the four induction tests as regards to the plasma concentrations of theophylline. After 6, 9 and 12 h, respectively, from administration of the drug, theophylline plasma levels between 7 and 9 micrograms/ml were found, which are to be considered more than satisfactory after an acute administration. A continuous protective activity has been noted against the exercise stress, with a significant difference between drug and placebo, for all lung function parameters with the obvious exception of the first one in which a satisfactory level of theophylline absorption was not reached. The finding of this new positive aspect of the drug investigated appears to be extremely interesting, particularly if added to the already well-known therapeutic activity, and to the fact that often other classes of drugs do not show a good correlation of protective action against EIA and prevention of spontaneous asthmatic attacks.

Adolescent↗

[Rehabilitation of the worker with bronchopneumopathy].

Epidemiological data show that chronic diseases of the respiratory apparatus have constantly increased over the last 20 years or so, often involving relatively young age classes. The increased survival rates due to chemotherapy also increase the importance of rehabilitation in such diseases. The officially accepted concept of a "global" rehabilitation is particularly significant in the case of patients of working age. The main rehabilitation procedures include chest physiotherapy, aerosol therapy, oxygen therapy (where selection criteria have been established and where there are new prospects related to long-term oxygen therapy), intermittent positive pressure breathing and physical retraining. Details on the methods of assessment and training and data concerning three groups of patients suffering from respectively chronic obstructive lung disease, silicosis and asbestosis, are given. The data show a general pattern of a decrease in ventilation (for an unchanged level of O2 uptake and CO2 output) and reflect a rise in muscular efficiency (exercising and respiratory) enabling the body to perform the same work load at a lower energy cost. The authors discuss the vocational rehabilitation of the patient with lung disease and illustrate the most useful procedures in the assessment of the subject, the environment and the place of work, including guidelines to achieve this. Rehabilitation treatment is also summarized into a number of stages, with the goals at different therapeutic levels and the ways to reach them.

Asbestosis↗