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Biomedical subjects

F Iseki

Publications and source records attributed to F Iseki.

At least 19 recordsLinked to original sources
PubMed1989

Arthroscopy after anterior cruciate reconstruction with the Leeds-Keio ligament.

The healing of anterior cruciate ligaments reconstructed with the Leeds-Keio artificial ligament was observed by arthroscopy in 42 knees and biopsy in 19 knees at intervals from 3 to 24 months after implantation. By three months the implant was covered with immature new tissue, and a dense vascular network crossed its surface. At 12 months a new ligament had developed and matured, looking like the natural one in most cases. Histology at this stage showed abundant collagenous fibres running parallel and longitudinally, while the synovial membrane showed no more than very slight inflammatory changes. By 18 to 24 months, the new ligament often had the arthroscopic appearance of a normal anterior cruciate ligament. These results suggest that this scaffold type of artificial ligament is effective for cruciate reconstruction, giving satisfactory healing without significant complications.

Adolescent↗
PubMed1989

A stress analysis of the proximal tibia after insertion of the endoprosthesis.

Detailed investigation for the local stress increment at the fixation post bottom of an artificial knee joint was performed by two-dimensional finite element method. A strain measurement was also conducted by wire strain gauges on a cancellous bone with a special method. It was made clear that a curvature with a certain extent of radius was necessary for the corner of a fixation post and application of acrylic cement with a certain extent of thickness (3 mm less than or equal to) was effective for stress relaxation, and that an optimum value (10(-1)-10 GPa) existed for elastic modulus of bone cement.

Biomechanical Phenomena↗
PubMed1981

Arthrographic study of the rheumatoid knee. Part 2. Articular cartilage and menisci.

The changes of the articular cartilage and of the menisci in 129 knee joints with classical rheumatoid arthritis have been investigated by an improved arthrographic technique. The changes of the intra-articular components on the arthrograms coincided well with direct views at arthroscopy and surgery. The changes of the articular cartilage on the arthrograms were graded as normal, deposit and pooling, thinning, filling defect, destruction, and disappearance, and those of the menisci as normal, degeneration, tear, and disappearance. The results showed that: (1) The radiographs did not always reflect the changes of those intra-articular components in the early stages; especially in stage 2 they showed various conditions from intact to destruction. (2) The changes of the menisci were less advanced than those of the articular cartilage in the early stages. (3) The changes in those components progressed almost symmetrically in both compartments. It is necessary to appreciate not only the pathological condition of the bones of the knee joints but also that of the intra-articular components to devise more careful programmes of treatment for rheumatoid knees.

Adult↗
PubMed1981

Partial resection of the discoid meniscus in the child's knee.

Seven children underwent partial meniscectomy for symptomatic discoid lateral meniscus. This procedure, modifying the discoid meniscus to the normal semilunar shape, was indicated only when degeneration or tear was minimal, when the meniscus was not abnormally thickened nor of Wrisberg type, when it was not hypermobile, when the capsular attachment was intact, and when the residual meniscus was free from abnormality. The results were excellent clinically, radiologically and arthroscopically, rehabilitation was shortened to half that required for total meniscectomy and the residual meniscus functioned entirely normally.

Adolescent↗
PubMed1980

[Clinical pictures of the osteoarthritis in the knee joint (author's transl)].

A total of 3,176 osteoarthritic knees are studied for the clinical course, and some of them are analysed for biomechanical development of the gonarthritis. Varus deformity, obesity, female incidence, patellar and medial femoral joint changes, and loss of range of motion are dominant in the clinical pictures of the gonarthritis. Joint effusion and instability are not principal manifestation. Meniscus injury, ligamentous involvement, and hip fusion have much effect on the development of the gonarthritis. Synovial degeneration increases in number by aging but idiopathic haemorrhage is rarely observed.

Adult↗
PubMed1979

The evaluation of plasma dopamine beta-hydroxylase activity in essential and secondary hypertension.

The relation of plasma dopamine beta-hydroxylase (DBH) activity to age was examined in normotensive and hypertensive subjects. Plasma DBH activity was the highest in the group of 25--34 years and gradually decreased with age. Plasma DBH activity was higher in the hypertensives than in the normotensives in all age groups, and the difference was significant between the groups of 45--54 and 55--64 years. Plasma DBH activity was increased in labile hypertension. Plasma DBH activity was higher in the group of essential hypertension with normal renal function than in that with reduced renal function. It was lower in the severe hypertensives than in the mild cases. Plasma DBH activity was also decreased in the hypertensive patients with cerebrovascular disorders. Plasma DBH activity was lower in the hypertensive patients with renal parenchymal diseases than those of essential hypertension with normal renal function. Plasma DBH activity was also decreased in primary aldosteronism, while it was increased in pheochromocytoma. These observations suggest that measurement of plasma DBH activity may be valuable in the differentiation of essential hypertension from the secondary forms of hypertension, and the evaluation of the hypertensive processes. To evaluate plasma DBH activity, it is important to consider its age-related changes.

Adult↗