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Biomedical subjects

F Iskander

Publications and source records attributed to F Iskander.

7 recordsLinked to original sources
PubMed1999

Lead and copper contamination of soil from industrial activities and firing ranges.

Lead still remains one of the most thoroughly investigated heavy metals in the environment. Although the identification of lead in soil is a routine matter, its environmental consequence is still much debated because of its potential mobility. We have investigated lead- and copper-contaminated soil from two different areas. One was in an urban area, which formerly had a lead smelter within the city. The other a firing range, in which hundreds of thousands of rounds were fired into a very large mound known as a berm. Homogeneity tests, depth profiles, and Pb-Cu correlations are discussed.

Copper↗
PubMed1987

Seasonal changes in the prevalence of Haemonchus and Trichostrongylus hypobiotic larvae in tracer goats in Malaysia.

An investigation into the seasonal changes in the population structure of Haemonchus and Trichostrongylus in tracer goats was conducted over 12 months at Serdang, an area in southern West Malaysia with year-round tropical rainfall. Successive groups of parasite-free tracer goats were grazed for a month alongside naturally infected adult goats and necropsied for worm counts 14 days after their removal from pasture. No hypobiotic larvae of Trichostrongylus were recovered. Hypobiotic larvae of Haemonchus were evident during each month of the year but accounted for only a very small proportion of the total Haemonchus burden. Very low levels were encountered from December through to June. Comparatively higher levels of hypobiosis were observed thereafter with a peak of 7.4% in September. The factors responsible for hypobiosis were not clearly defined but the phenomenon was associated with increasing levels of soil moisture storage. Host resistance, adult worm population of tracers and population of ingested L3 were ruled out as possible inducing factors.

Animals↗
PubMed1987

Experimental study on developing rat kidney after Naja haje envenomation.

In the present experiment 164 pregnant white Wistar rats were used to study the effect of Naja haje (Egyptian cobra) venom on the developing kidney. The rats were divided into 3 groups; a control group, a group receiving one LD50 of N. haje venom and the third injected with 1/8 of LD50. The injection was performed at different stages of gestation. After birth, the neonates of group I and III and embryos of group II were examined histologically, histochemically and electron-microscopically. Both lethal and sublethal doses of N. haje venom produced haemorrhages and vascular congestion of the developing kidney. The lethal dose had degenerative effects on the podocytes and endothelium. Tubular damage appeared mainly as mitochondrial degeneration and bud-like extension, protrusions of cytoplasm and vacuolization. The succinic dehydrogenase enzyme showed decreased activity. The sublethal dose had an effect on the glomerular basement membrane in the form of splitting, increased mesangial cells and matrix, mitochondrial degeneration and fusion of podocyte processes. Tubulization of the parietal epithelium, vacuolization of the proximal tubules, mitochondrial degeneration and apical budding were evident.

Animals↗