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Biomedical subjects

F J Barbado

Publications and source records attributed to F J Barbado.

At least 55 records · Page 3Linked to original sources
PubMed1989

[The spectrum of lymphadenopathy in HIV-positive patients. Prospective analysis of 45 cases].

In the prospective analysis of 45 patients (intravenous drug addicts and homosexuals) with lymphadenopathy and positive HIV virus titers, including serology, immunological and histological lymph node studies, we examined the etiology and diagnostic results of the methods used. We found 19 cases with lymphoid follicular hyperplasia, 9 with lymph node tuberculosis, 7 with lymphoid depletion, 2 non-Hodgkin's lymphoma and one case with Hodgkin's disease. Routine serology did not provide more information concerning the lymphadenopathy and the immunological study showed a relationship, however not lineal, between the immunosuppression and the stage of HIV infection, while the histologic diagnosis did not, except in the cases with lymphoid depletion and non-Hodgkin's disease. In the asymptomatic patients (10 cases) biopsy results did not change the given treatment as well as the prognosis, thus, it could be eliminated in a routine study. Biopsy on occasions implied therapeutic management (lymph node tuberculosis) or a change in prognosis (lymphoma or lymphoid depletion) in symptomatic patients (35), therefore, it seems to de justified. Fine needle aspiration of the lymph nodes was harmless and safe and was shown to have good sensitivity (79%), thus, it can be recommended as a first elective diagnostic method for lymph node histology.

Adult↗
PubMed1987

Coagulation abnormalities in patients with eosinophilia.

Haematological variables in patients with eosinophilia and in healthy control subjects were studied in order to determine whether there were abnormalities in the coagulation system in patients. We found significantly elevated levels of fibrinogen, fibrin degradation products, platelet number and beta-thromboglobulin in patients. The abnormalities were not related to the causes of eosinophilia nor to its severity. This lack of correlation could be due to the heterogeneity of human peripheral blood eosinophils.

Blood Coagulation↗
PubMed1985

Mitral and aortic regurgitation in Behçet's syndrome.

A 35-year-old man with definite Behçet's disease developed acute mitral and aortic regurgitation. Valvular disease, we believed, was another manifestation of this disease. Cardiac involvement in Behçet's disease and the role of prednisone therapy are discussed.

Adult↗
PubMed1985

The spectrum of neurological manifestations in myeloma.

Thirty-two patients with myelomatosis (3 with a solitary plasmocytoma and 29 with multiple myeloma) and neurological complications, from a group of 110 unselected patients with myelomatous disease were recorded. Spinal cord compression was the most frequent complication seen in 12 cases. In 9 subjects, it was the presenting symptom, and in 11 cases was caused by extradural plasmocytoma of the thoracic spine. Early decompressive laminectomy was curative in 3 cases, but in the rest, delay in diagnosis resulted in only partial recovery even with radiotherapy. Of the 6 patients with nerve root involvement, radiotherapy led to full recovery in 2 of 3 cases, and laminectomy resulted in complete improvement in 2 other cases. Peripheral polyneuropathy was seen in 8 cases, 2 related to systemic amyloidosis and 6 unassociated with amyloidosis. Both forms of neuropathy shared a slow progression, independent of the course of the myeloma. Acute encephalopathy, found in 6 cases, was due to hypercalcemia and/or serum hyperviscosity, and led to a significant shortening of mean survival. One patient had third cranial nerve palsy due to the overlying lesion of the skull base, and another suffered acute bacterial meningitis.

Aged↗
PubMed1984

Fever of unknown origin: a survey on 133 patients.

The hospital records of one hundred and thirty-three patients with fever of unknown origin (FUO) were studied. An etiologic diagnosis had been made in 105 patients: 41 patients had an infection, 24 had a neoplasm, 17 had a connective tissue disease, and 23 had various diseases grouped under "miscellaneous." FUO was self-limiting in 25 of the remaining patients. Invasive procedures (arteriography, biopsy, laparoscopy, paparotomy) were necessary to establish a diagnosis in 67 patients, non-invasive tests (sero-immunologic, bacteriologic, conventional radiologic tests, clinical course and treatment response) were sufficient in 27 patients. In 11 patients, the cause of FUO was determined in necropsy. Thirty patients died of FUO: 6 patients with a neoplasm, 4 with a connective tissue disease, and 7 with diseases termed miscellaneous.

Adolescent↗