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Biomedical subjects

F J Carapeto

Publications and source records attributed to F J Carapeto.

At least 19 recordsLinked to original sources
PubMed2006

Foreign body post-varicella granulomas due to talc.

Foreign body granulomas in the skin have been described frequently and may have various causes. Diagnosis is relatively easy in most cases, as most are related to foreign material penetrating into the skin due to different kinds of traumas. We present the case of a boy with multiple facial granulomas, persisting more than 6 months and related to the use of topical anti-pruriginous talc powder applied to papuloexudative lesions caused by varicella. Data gathered in the anamnesis, examination with polarized light and images seen through the electron microscope enabled us to identify the causal agent talc as the inducer of the granulomatous lesions that the patient presented, discarding other types of foreign body granulomas of exogenous origin.

Administration, Topical↗
PubMed2002

Recurrent lentigo maligna as amelanotic lentigo maligna melanoma.

Amelanotic lentigo maligna and lentigo maligna melanoma are extremely rare tumours. Even rarer is a recurrent amelanotic lentigo maligna or amelanotic lentigo maligna melanoma at the site of a previously removed pigmented lentigo maligna. We describe two cases of recurrent amelanotic lentigo maligna melanoma manifesting as erythematous plaques evolved from previously excised pigmented lentigo maligna.

Aged↗
PubMed2000

Primary tuberculous chancre caused by Mycobacterium bovis after goring with a bull's horn.

A 14-year-old boy was gored by a bull during festival celebrations. The horn of the bull caused a wound on his left hand and after 3 months it was a accompanied by an ulcerated nodule on the left upper arm and an axillary adenopathy. The tuberculin test was positive and a culture of the aspiration biopsy specimen of the axillary lymph node yielded Mycombacterium bovis.

Adolescent↗
PubMed1999

Epidermal naevus syndrome and hypophosphataemic rickets: description of a patient with central nervous system anomalies and review of the literature.

The epidermal naevus syndrome (ENS) is a rare dermatological condition consisting of congenital epidermal nevi associated with anomalies in the central nervous system, bones, eyes, hear or genito-urinary system. We report a new case of ENS associated with hypophosphataemic rickets. The girl was born with a mixed-type epidermal naevus and skeletal anomalies. Hypophosphataemic rickets was diagnosed at the age of 2.5 years. At 14 years of age. MRI of the head demonstrated right brain hypotrophy, a left temporal arachnoid cyst and asymmetric lateral ventricles. We reviewed the literature and found 13 reported cases of ENS associated with hypophosphataemic rickets. Conclusion We report a further patient with epidermal naevus syndrome and hypophosphataemic rickets, followed from birth to the age of 15 years, who had structural central nervous system anomalies with normal intellectual functioning. A comprehensive neurological work up is recommended in patients with epidermal naevus syndrome.

Adolescent↗
PubMed1998

Visceral leishmaniasis with cutaneous lesions in a patient infected with human immunodeficiency virus.

We report a case of visceral leishmaniasis (VL) with cutaneous lesions in a patient infected with human immunodeficiency virus (HIV). The cutaneous lesions consisted of erythematous papules on the legs. Biopsy of one lesion showed abundant Leishmania amastigotes within epithelial cells of an eccrine sweat gland in the dermis. Leishmania organisms were also found in a blood smear. Rapid and complete clearance of the cutaneous lesions was achieved after antimony therapy. Cutaneous lesions in VL are being reported increasingly frequently in patients with HIV infection and their significance remains in discussion.

AIDS-Related Opportunistic Infections↗
PubMed1995

Improvement of scleredema associated with IgA multiple myeloma after chemotherapy.

The presence of a monoclonal gammopathy in patients with chronic scleredema is a recently described, unusual association of unknown significance. There have been very occasional reports of multiple myeloma in such patients. We now report a patient with long-standing scleredema who developed an IgA-kappa multiple myeloma. Once chemotherapy for the myeloproliferative disorder was instituted, scleredema improved significantly, suggesting a pathogenetic link between the two conditions.

Aged↗
PubMed1989

[Menkes syndrome: study of 2 new cases].

The authors describe two new cases of Menkes' syndrome, both of which belong to the same family. Clinically, one of them began with a convulsive encephalopathy and the most significant features observed in the other were psychomotor delay and changes in the hair. In both cases, the quantity of copper and ceruloplasmin was very low. A description is given of the clinical, electroencephalographic and radiological findings and a microscopic study of the hair. One of them died at the age of 16 months and the other is at present 2 5/12 years old and demonstrates a serious psychomotor delay. Given the inefficiency of the treatment, genetic counsel and prenatal diagnosis are the only useful alternatives for the control of this phenomenon.

Brain Diseases, Metabolic↗
PubMed1988

[Cutaneous mycobacteriosis caused by Mycobacterium chelonei var. abscessus].

We are commenting on a case of cutaneous mycobacteriosis (M. chelonei) in an asthmatic 60-year-old patient under continuous steroid treatment, who months after an accidental trauma on his hand, developed painful papular lesions, located over the trauma scar, and on the dorsal lateral side of the forearm. The lesions on the forearm were accompanied by epitrochlear adenopathies and a general reaction in the form of fever. Histologically the lesions showed a subacute inflammatory reaction with lymphocytes, histiocytes, polynuclear neutrophils and areas of necrosis. The staining of the exudate with Ziehl-Neelsen and the histological samples were negative, but the culture was identified as M. chelonei, of the abscessus variety. The process was cured with continuous therapy with cefotaxime and procodazol.

Benzimidazoles↗
PubMed1988

[Fixed cutaneous sporotrichosis localized on the face, with an infrequently seen clinical picture].

A case of fixed cutaneous sporotrichosis in an urban patient in whom the contagious trauma could not be proved is commented on. Remarkable is the location of the lesions involving the face, which is extremely rare, as well as the morphology of the lesions, adopting the pattern of congestive erythema on which there were crusty-erythematous papules causing an intense itching which also preceded their onset.

Dermatomycoses↗
PubMed1988

[Diffuse normolipemic xanthoma planum].

We comment on the case of a 75-year-old woman whose dermatologic process had started 15 years before with the onset of xanthelasma on the lower eyelids which were surgically removed, recurring on the scar areas two months later. At the same time new lesions involved the forehead as well as the periorbital and malar regions. Some months later new yellow papular lesions appeared involving the neck, thorax, pelvis and extremities which grew eccentrically covering large areas. Five years later the lesions localized on the face and showed a progressive tendency to atrophy in their centers while those localized on the trunk showed an evolution to sclerosis of their central area. There was no mucosal involvement or ulceration in any of the xanthomatous lesions. The microscopic study revealed the existence of a dermal infiltrate formed by histiocyte foamy frothy cells and Touton cells, among which there were some lymphocytes, which occasionally adopted a perianexial, perineural and perivascular pattern but there were no signs of thrombosis or degenerative changes in the perilesional connective tissue. The study by chromatography of the lipid composition of the pathologic skin revealed an increase in cholesterol esters. The laboratory exams as well as the general physical examination performed every six months for a period of 15 years' time were always normal except for a moderate elevation of ESR which persisted throughout the process.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1985

[Dermatomycosis in plaques caused by Botryomyces caespitosus. A new causative agent].

The clinical and histological features of a dermomycosis caused by a new dematiaceum fungus are described. The mycological characteristics of this fungus individualize and differentiate it from other demiataceum hyphomycetes, proposing the name of Botryomyces caespitosus for it. The submicroscopic features are commented, as well.

Accidents, Occupational↗
PubMed1985

[Toxic epidermal necrolysis (Lyell's syndrome) caused by piroxicam, with fatal outcome from disseminated aspergillosis].

A case of Lyell Syndrome provoked by ingestion of an antirheumatic drug (Piroxicam) is commented. The evolution under treatment with steroids and broad spectrum antibiotics was excellent but once recovered from this, the patient died subsequently to a systemic infectious process caused by an Aspergillosis with pulmonary involvement and secondary affectation of the kidneys, brain liver, and heart. The hepatic involvement during the acute stage is discussed and evaluated (increase of transaminases), amylasemia, amylasuria, anemia and thrombopenia which persisted throughout the process and presumably conditioned the evolution of the disease.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMed1985

[Generalized urticaria due to food allergy (codfish)].

A case of generalized urticaria after ingesta of raw cod in a patient who had any previous episodes of atopy or other findings of interest is presented. One month after the manipulation of this same food she presented another episode of generalized urticaria, this time more severe and persistent. Skin patches to cod provoked a contact urticaria probably produced by an immunologic mechanism. A sensitization via the digestive tract is presumed on the basis of the clinical course and the symptoms of the patient.

Animals↗
PubMed1985

[Infantile and progressive papular mucinosis].

We comment the histologic and clinical features of a process studied in a 2-year old patient with neither clinical nor laboratory evidence of any other disease, being characterized by the existence of multiple papules, grouped but not confluent, asymptomatic, skin-coloured or slightly erythematous and located on the lumbar area. The outset of the lesions occurred at birth and their number has increased all through the first two years of file. The histologic image is consistent with mucin focus in the middle dermis, relatively well limited but without a perilesional capsule, associated to a fibroblast proliferation. The case is considered to be a reactive modification of fibroblasts with an alteration of their secretory capacity, which causes an increase of mucin with a decrease in the connective fibrillar components. The differences of this process with other primary or secondary cutaneous mucinosis especially with focal mucinosis are discussed. The non-specificity of the clinical features, makes it necessary to carry out the microscopic examination to get the correct diagnosis, being the surgical excision of the lesion the treatment of choice.

Diagnosis, Differential↗