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Biomedical subjects

F J Frensilli

Publications and source records attributed to F J Frensilli.

8 recordsLinked to original sources
PubMed1987

2,8-Dihydroxyadenine urolithiasis: report of an adult case in the United States.

2,8-Dihydroxyadeninuria is a rare purine metabolic disorder that has been reported to have caused urolithiasis in 14 cases, mostly children. Excretion of the hydroxylated metabolites of adenine results from a deficiency of adenine phosphoribosyltransferase. The insoluble calculi have a similar chemical structure to uric acid and frequently are misdiagnosed as uric acid calculi. Management differs from that of uric acid urolithiasis. We report on an adult with 2,8-dihydroxyadenine urolithiasis in the United States.

Adenine↗
PubMed1981

The myth of the clean catch urine specimen.

Urine specimens obtained from unprepped ambulatory females who voided into an unsterile disposable plastic cup showed a 95-per cent correlation with a catheterized specimen collected from a prepped patient through a sterile cystoscope. From these data, it appears that the midstream urine specimen and its unpleasant collection routine can be eliminated. We have found that specimens collected at anytime during voiding in unsterile disposable plastic cups result in reliable urine cultures.

Adult↗
PubMed1981

Changing parameters of donor semen.

Effective contraception and easily available abortion have contributed to the decline of adoptable children. This decline has resulted in a marked increase in the demand for AID. The provider of donor semen must establish minimal semen criteria to meet this demand effectively. During the past 8 years the authors have found a declining trend in several parameters of donor semen. Sperm count has decreased steadily, but not motility. Forward progression, viability, and morphologic characteristics have also shown a declining trend. The authors have had to reject a greater number of potential candidates in each ensuing year to exceed their minimal semen criteria. Despite the higher rejection rate, the authors have not been able to maintain the higher sperm parameters seen in the earlier years. The authors project that in 5 or 6 years, if the trend continues, no potential donor will meet their current minimal standards.

Cell Survival↗