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F J Hodges

Publications and source records attributed to F J Hodges.

46 records · Page 3Linked to original sources
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Leigh disease (subacute necrotizing encephalomyelopathy): CT and MR in five cases.

Magnetic resonance (MR) imaging and CT were used in supporting the diagnosis of Leigh disease (subacute necrotizing encephalomyelopathy) in five patients. Two cases were confirmed at postmortem examination, and three patients have laboratory and/or clinical histories suggestive of Leigh disease. Four cases demonstrated findings in the basal ganglia, especially the putamina, with symmetrical areas of low attenuation on CT. Correspondingly, on proton saturation and T2-weighted pulse sequences, these areas showed high intensity signal characteristics by MR. Similar findings were noted in the caudate nucleus (two cases). Magnetic resonance proved to be superior to CT in establishing other areas of involvement: tectum and tegmentum (one case) and medullary olive (one case). Pathology identified these lesions as representing necrosis. Magnetic resonance may be diagnostic in the appropriate clinical setting.

Brain↗
PubMedDate not supplied

Neurodegenerative diseases of childhood: MR and CT evaluation.

To evaluate the diagnostic utility of MR and CT in neurodegenerative diseases of childhood, we examined 63 children (MR in 44, CT in 53) carrying diagnoses of Leigh disease (14 patients), various metabolic diseases (13 patients), leukodystrophies (13 patients), other specific degenerative diseases (10 patients), and unclassified neurodegenerative disorders (13 children). Magnetic resonance yielded positive findings in 86% and CT in 81%. Lesion extent and conspicuity were consistently greater with MR. The high frequency of abnormalities detected on MR, and to a lesser extent on CT, helps distinguish children with neurodegenerative diseases from those with nonprogressive idiopathic movement disorders. The most common abnormalities included signal alterations (MR) or decreased attenuation (CT) of the basal ganglia and cerebral white matter, as well as local or generalized brain atrophy. Although considerable overlap was present, the findings showed four general patterns that may assist in tentative classification of patients with nonspecific clinical and laboratory findings.

Adolescent↗
PubMedDate not supplied

Limited coronal CT: an alternative screening examination for sinonasal inflammatory disease.

Coronal CT is the definitive procedure for radiologic evaluation of sinonasal inflammatory disease, yet many clinicians rely on the less expensive plain film sinus series. We designed a limited four slice coronal CT and prospectively compared it with conventional coronal CT and plain film sinus series in 25 patients to determine whether a limited CT examination is a suitable alternative to these other radiologic procedures in screening for sinonasal inflammatory disease. The presence, amount, and location of mucous membrane disease, opacification, air fluid levels, retention cysts, erosions, and anomalies were recorded for each technique. The limited CT agreed with the complete CT in 82% of the 200 sinus compartments reviewed. Localized disease, usually mucosal thickening of 3 mm or less and missed on the limited CT, but detected on the complete CT, accounted for 22 of 36 errors of interpretation. Underestimation of mucosal disease, usually 2 mm or less, accounted for eight errors and misinterpretation of partial volume effect for three errors. Using complete CT a s the established standard, plain film missed 37 instances of disease detected on the limited CT; 73% involved an error of mucosal thickening 4 mm or greater. A limited coronal CT of the paranasal sinuses offers a potentially lower cost alternative to complete CT in screening for sinonasal inflammatory disease. It is more accurate than plain film series. Localized disease and osteomeatal disease is underestimated with the current protocol, and so a limited CT should not be used for evaluating potential cancer patients or for surgical planning.

Adult↗
PubMedDate not supplied

Quo vadis, Doctor?

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Michigan↗
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Lateral disk herniation into the lumbar intervertebral foramen: differential diagnosis.

Lateral disk herniation into the intervertebral foramen if not recognized may result in a negative surgical exploration. The condition is readily recognized by computed tomography (CT), which demonstrates a soft-tissue mass in the intervertebral foramen, focal protrusion of the posterolateral margin of the disk into the foramen, absence of dural sac deformity, and occasionally the presence of calcium or gas in the intervertebral foramen. The differential diagnosis includes metastatic neoplasm, primary neoplasm, and conjoined root sheath anomaly. Features that enable CT differentiation of these conditions from lateral disk herniation are described. Myelography is useful in the identification of a conjoined root sheath.

Diagnosis, Differential↗