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Biomedical subjects

F J Ingelfinger

Publications and source records attributed to F J Ingelfinger.

At least 181 records · Page 10Linked to original sources

The role of sodium in intestinal glucose absorption in man.

The effect of luminal sodium on intestinal glucose absorption at a variety of glucose concentrations was studied with a segmental perfusion technique in normal subjects. Uphill glucose transport was inhibited with sodium-free perfusions with either mannitol or Tris-HCl as the osmotic replacement of sodium (P < 0.01-P < 0.001). This effect did not appear to be the result of solvent drag, as increasing net water absorption without supplying sodium to the lumen did not increase glucose absorption. Downhill glucose transport (infusion concentrations of 6.0-27.8 mmoles/liter), on the other hand, was not affected by the absence of sodium in the infusion solution. Glucose concentrations of upper intestinal fluid after normal carbohydrate meals were usually found to exceed serum concentrations; thus, downhill glucose absorption, with, at most, a very limited dependence upon intraluminal sodium concentration, may account for a significant part of normal carbohydrate absorption.

Adolescent↗

Austere librarians--volte-face.

Medical Libraries are too concerned with their customers and not interested enough in their wares. The number, nature, behavior, and satisfaction of readers and the book use by readers are extensively analyzed. Though important for library operation, such studies tend to make library staff regard and treat readers as impersonal members of a study population. As opposed to critical analysis of readers, little effort is made in this direction with respect to journals. It is, therefore, proposed that medical libraries take a hard look at the journals they offer and classify and display them in A, B, C, and D categories. The following benefits might be envisioned: the reader would be helped in looking up a subject that is not in his immediate field of specialization, the occupancy of valuable space by poor journals would be prevented, medium quality journals would strive to improve themselves, and it is even possible that poor and superfluous journals would be put out of business.

Classification↗