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Biomedical subjects

F J Manero Ruiz

Publications and source records attributed to F J Manero Ruiz.

10 recordsLinked to original sources

[Bone Paget's disease in the young adult].

FOUNDATION: Bone Paget's disease (BPD) is a focal disorder of bone remodeling of unknown etiology that affects mainly patients older than 50 years. BPD is after osteoporosis the most frequent osteopathy of the western world and was described for the first time in 1876 by Sir James Paget who called it osteitis deformans. PATIENTS AND METHODS: We present two patients with BPD younger than 40 years. In this report their clinical, analytical, diagnostic, and therapeutic manifestations are described, with the findings of bone biopsy in one of them. Is noteworthy to us the younger age of the patients, rare for this disease, which means that we have carried out the follow-up of the cases. CONCLUSION: In a young adult with high phosphatase alkaline values we will include BPD in the differential diagnosis.

Adult↗

[Pneumonitis caused by gold salts in psoriatic arthritis: report of 2 cases].

The gold-salts compounds have been used for the treatment of rheumatoid arthritis and of psoriatic arthritis, they are generally tolerates and when have adverse effects they are minor. The gold-induced lung toxicity is a infrequent adverse effect of patients with rheumatoid arthritis characterized by three types: interstitial penumonitis, bronchiolitis obliterans with organizing pneumonia and bronchiolitis obliterans, usually the first is the more frequent. The diagnostic is supported by the clinical manifestations, chest roentgenogram, bronchoalveolar lavage fluid and chest computed tomography scan. Biopsy study of the lung, is only needed for exclusion of other pulmonary disease. The gold-induced lung toxicity in the psoriatic arthritis is rarelly described, we report two cases with gold-induced pneumonitis with benign clinical course after cessation of therapy and treatment with corticosteroids.

Antirheumatic Agents↗

[Spinal pseudoarthrosis in ankylosing spondylitis].

Spinal pseudoarthrosis is an uncommon complication in patients with advanced ankylosing spondylitis which consists in destruction of the discovertebral junction. Two cases of spinal pseudoarthrosis at the thoracolumbar level after a spontaneous fall are reported. Because of the neural arch involvement and the spinal cord compression a stabilization was required. Different imaging techniques are complementaries in the study of this entity, conventional radiographs and computed tomography may depicte bone abnormalities, but magnetic resonance allows a correct evaluation of spinal cord and soft tissue involvement.

Humans↗

[Acute polyarthritis associated with parvovirus B19 infection].

We describe one female with acute polyarthritis and transitory rash. The arthritis of sudden onset, is localized in large and small joints and accompanied by significant stiffness, particularly noted in early morning. The symptoms only improvement a few with nonsteroidal anti-inflammatory drugs and the arthritis resolved within a few days. The diagnosis is based in the presence of anti-B19 IgM. The differential diagnosis of the acute polyarthritis is extensive, serological test should be made when we suspect the presence of a viral arthritis.

Acute Disease↗

[Atypical algodystrophy of the knee: apropos 2 partial cases].

Algodystrophy is a common entity which may present in many clinical contexts. Its early diagnosis and therapy are of great prognostic interest. Apart from the typical complete forms there are some other atypical forms, such as partial knee algodystrophy, of difficult diagnosis. Its inclusion in the differential diagnosis of gonalgia occurring in patients attended under many medical specialties is therefore necessary. Two atypical cases of knee algodystrophy in its partial form are reported. One of these cases relapsed at the heterolateral knee after 18 months of the initial presentation; this second episode was also a partial form, a fact which we have not seen reported. The reported cases are here discussed and the scarce literature is reviewed, commenting on the difficulty of the early diagnosis compared with other entities which may mimic the clinical picture, radiological and scanning features of algodystrophy, such as aseptic osteonecrosis or stress fracture. The diagnostic algorithm is discussed, pointing to the usefulness of magnetic resonance (MR) in difficult cases to rule out other entities which would entail different therapeutic modalities.

Aged↗

[The SAPHO syndrome or psoriatic arthritis: a complicated differential diagnosis. Apropos 3 cases].

SAPHO syndrome is characterized by osteoarticular involvement of ventral chest wall in the form of sternocostoclavicular osteoarthritis and hyperostosis and skin changes such as palmoplantar pustulosis and acne. Occasionally, psoriatic lesions and sacroiliitis are observed. However, despite the higher frequency of psoriasis in this syndrome, its inclusion in psoriatic arthropathy spectrum is not clearly established. The authors report three cases of SAPHO syndrome in psoriatic patients commenting on the difficulty in differentiating this entity from psoriatic arthritis as well as its relationship with seronegative spondyloarthropathies. This disease has been described mainly in Japan and only a few cases of this disease have been reported in the European or American literature.

Acne Vulgaris↗