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F J Muñoz Negrete

Publications and source records attributed to F J Muñoz Negrete.

8 recordsLinked to original sources
PubMed2003

[Frequency-doubling perimetry in retrochiasmatic disorders].

OBJECTIVE: To determine the ability of frequency doubling technology (FDT) to evaluate retrochiasmatic lesions. METHODS: 21 patients with characteristic retrochiasmatic visual field defects in automated perimetry (Humphrey field analyzer, 24-2 SITA) underwent FDT using C-20 screening and threshold tests. Two independent observers described the visual field defects, the degree of congruence and macular sparing of the three explorations. RESULTS: The visual field defect found in the 24-2 test was inferred in 63.2% and 70% of the eyes from the C-20 screening and C-20 threshold test respectively. The retrochiasmatic lesions were congruent in 45% of the cases in automated perimetry, 5.6% in C-20 screening and 15% in C-20 threshold test. Macular sparing was present in 45% of cases with automated perimetry, 89% with C-20 screening and 82% with C-20 threshold test. CONCLUSIONS: The FDT allows us to suspect retrochiasmatic lesions in more than one-half of patients, but it tends to underestimate the defects. It is not useful for detecting macular sparing or the evaluation of visual field congruence. Both FDT strategies offer similar results, so the C-20 screening test could be more advisable because of its speed (mean: 70 seconds). However, in retrochiasmatic lesions the FDT accuracy is considerably lower than the 24-2 SITA strategy.

Female↗
PubMed2003

[Non-penetrating deep sclerectomy combined with phacoemulsification. Results and complications].

PURPOSE: To evaluate the efficacy and safety of phaco-deep nonpenetrating sclerectomy (PDNS) with reticulated hyaluronic acid implant for glaucoma combined surgery. MATERIAL AND METHODS: Noncomparative retrospective study of 39 eyes of 36 patients who underwent PDNS. Preoperative and 1, 7 days, 1, 3, 6 and 12 months after surgery data retrieved were best-corrected visual acuity, intraocular pressure (IOP), number of glaucoma medications and intra and postoperative complications. RESULTS: Mean preoperative IOP was 23.1 mm Hg (SD: 8.8). Statistically significant reduction in IOP was observed in all postoperative visits (P = 0.000); a mean IOP reduction of 8.63 mm Hg (SD: 8.55) and 6.88 mm Hg (SD: 5.46) was found 6 and 12 months after surgery respectively. Mean percentage of IOP reduction was 32.78% (SD: 21.30) and 27.74% (SD: 18.15) six and twelve months after surgery respectively. Mean preoperative number of glaucoma medications was 1.76 (SD: 0.85). In all postoperative visits a statistically significant reduction in the number of glaucoma medications was observed (P = 0.000). One year after PDNS, mean number of antiglaucoma drugs was 0.34 (SD: 0.60), and 71.9% of the eyes did not need any glaucoma medication. Predetermined target IOP was achieved in 84.2% of the eyes. A gain of almost 3 lines of mean VA was observed one year after surgery. Severe inflammatory reaction (7.7%) and hyphema (5.1%) were the most frequent observed complications. CONCLUSIONS: These preliminary results suggest that PDNS could be a safe and effective surgical technique for combining glaucoma and cataract surgery.

Aged↗
PubMed2002

[Automated perimetry and neuro-ophthalmology. Topographic correlation].

Visual fields continue to be a key exploration for the diagnosis and follow-up of patients in neuro-ophthalmology. The pattern of visual field defects helps, and in many cases allows, the identification of brain damage location. Manual kinetic perimetry has been replaced by automated methods. 24-2 SITA (Humphrey Visual Field Analyser) and TOP (Octopus) are regarded as the standard perimetric explorations in neuro-ophthalmology. Goldmann perimetry remains as an useful exploration for temporal crescent detection in occipital lobe diseases, and it could be more accurate and consistent for studying lesions in the post-geniculate pathway. Frequency doubling perimetry could be useful for detecting neuro-ophthalmic visual field defects, but does not provide an accurate characterisation of the lesions. From the neuro-ophthalmic point of view, visual field defects could be divided in pre-chiasmatics, chiasmatics and post-chiasmatics. Pre-chiasmatic defects are strictly unilateral, do not respect the vertical meridian, often have a nasal step associated and are usually accompanied by ocular pathology detectable in an ophthalmic examination. The characteristic perimetric pattern of chiasmal disease is bi-temporal hemianopsia. Homonymous contralateral defects are the characteristic perimetric pattern of post-chiasmal disease, and their congruency increases when the lesions are closer to the occipital lobe. Neuroimage studies are mandatory in all patients with a perimetric defect pattern compatible with chiasmal or post-chiasmal lesions. Magnetic Resonance Imaging may be normal in a patient with homonymous defects in Alzheimer's disease, the Heidenhain variant of Creutzfeldt-Jakobs disease, carbon monoxide poisoning and mild occipital ischemia demonstrated by SPECT or PET imaging (Arch Soc Esp Oftalmol 2002; 77: 413-428).

Humans↗
PubMed1992

Bilateral optic atrophy in Kenny's syndrome.

We present a 12-year-old girl with Kenny-Caffey syndrome and bilateral optic atrophy. The results of testing in this patient and the ocular findings in the 25 previously reported cases with Kenny-Caffey syndrome are reviewed. This is the first case with such an association in the literature to date.

Abnormalities, Multiple↗
PubMedDate not supplied

Botulinum toxin treatment of Hertwig-Magendie sign.

Hypertropia, not due to the usual causes and associated with a central nervous system disorder, should be suspected as being a skew deviation (Hertwig-Magendie sign). We describe a new case of this supranuclear disorder, presumably related to cocaine-induced stroke. This disorder was treated by botulinum A toxin (Oculinum) injection into the superior rectus muscle. Follow-up one year later found the vertical deviation resolved.

Adult↗