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Biomedical subjects

F J Roberts

Publications and source records attributed to F J Roberts.

18 recordsLinked to original sources

MCQ assessment of introductory clinical course for fourth year medical students.

A 60-item MCQ as administered to 46 fourth year medical students at the beginning, half-way, and at the end of a five week introductory clinical course. The stated goals were achieved: (1) a baseline measure was provided, indicating abilities brought by newly-arriving students; (2) data gave opportunity for "mid-course" corrections by students in their study and by tutors in their teaching; (3) overall student change was assessed, offering a measure of the educational effectiveness of the course, and (4) tutors were made aware of individual students requiring particular attention. Such assessment techniques provide an effective monitoring and motivating instrument at this level of medical education.

Education, Medical, Undergraduate

Yeast in blood cultures. Evaluation of factors influencing outcome.

Sixty episodes of candidemia occurring between January 1987 and September 1989 were retrospectively reviewed and the outcome was compared for three patient categories: neutropenic, postsurgical, and nonneutropenic nonsurgical. Because of increasing reports of resistant yeasts, minimal inhibitory concentrations (MICs) to amphotericin B (amB) were determined to examine its relationship to patient outcome. No significant differences between patient categories were found for selected risk factors, mortality, or species isolated, although there was a tendency for Candida tropicalis to occur in neutropenic patients. Statistical analysis using logistic regression showed that both an amB dose greater than 500 mg and a yeast MIC greater than 0.78 micrograms/ml were independent prognosticators of patient outcome.

Adult

Fatal trichosporonosis is not related to tolerance to amphotericin B.

A case of disseminated trichosporonosis in a 45-year-old female suffering from acute lymphocytic leukaemia is reported. The patient died of that mycosis despite of therapy with amphotericin B for which the pathogen had been proven susceptible in vitro.

Amphotericin B