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Biomedical subjects

F J Woodroffe

Publications and source records attributed to F J Woodroffe.

9 recordsLinked to original sources

Glycosylated haemoglobin as an alternative to the glucose tolerance test for the diagnosis of diabetes mellitus.

A comparison was made between the results of a standard 75 g oral glucose tolerance test and total haemoglobin A1 in 168 subjects referred by their general practitioners for the diagnosis of diabetes mellitus. The subjects were classified as having normal, impaired or diabetic glucose tolerance using WHO criteria. Of 108 subjects with normal glucose tolerance only three had haemoglobin A1 concentrations over 8%. Of 10 with impaired glucose tolerance two had haemoglobin A1 concentrations over 8%. Of 47 with diabetic responses, eight had haemoglobin A1 concentrations below 9%. There was a significant difference between the haemoglobin A1 concentration when fasting and that 2 hours after the glucose load in the subjects with a diabetic glucose tolerance response, but no significant difference between the two values in the other subjects.

Adolescent↗

Prolactin and impotence in diabetes mellitus.

A study was undertake to determine whether impotence in some diabetic patients might be due to a coincidental prolactinoma and therefore be potentially treatable. Of 83 consecutive men attending a diabetic clinic, three were found to have persistent mile to moderate hyperprolactinaemia. None of the three was impotent or taking any drug know to be associated with elevated serum prolactin, and anterior pituitary responses and pituitary fossa tomograms did not reveal any abnormality. The mean serum prolactin concentration of the 37 insulin-treated men was not significantly different from that of the 46 men on diet with or without anti-diabetic tablets, nor was there any significant difference between the mean serum prolactin concentrations of the 19 impotent men and of the 64 non-impotent men.

Adolescent↗

Computer-held clinical record system. II. Assessment.

A real-time medical recording system installed in two general medical wards has proved to be unacceptable to many of the ward staff. Reasons for this include operational problems, such as the impossibility of providing a 24-hour service, and conceptual problems, such as the difficulty of adapting the method for recording case histories. It is suggested that an outpatient department might have been a better site for this trial, and that deliberate instruction in medical recording should be given to students as a prerequisite to successful computer record keeping.

Attitude of Health Personnel↗