Biomedical subjects

F Jacqueline

Publications and source records attributed to F Jacqueline.

18 recordsLinked to original sources

PubMed1990

Pathology of the capsular and synovial hip nerves in chronic hip diseases.

Nerves of the synovial membrane and of the capsule of the hip have been studied with the usual techniques of optical neuropathology. We studied 52 hips from 46 patients: 13 hips of post-fracture states of the femoral neck, 13 hips of idiopathic osteonecrosis, 6 hips of rheumatoid arthritis, 6 hips of ankylosing spondylitis and 14 hips of osteoarthrosis. Small capsular and synovial nerves mainly located close to blood vessels are modified by the lesions of the surrounding tissue (inflammatory, vascular, traumatic and mechanical disturbances). The degree of involvement is related to the disease and its evolution. The peri- and endoneurium is thickened and demyelination is mostly observed. Nerve lesions begin focally and for some time are segmental. The final lesions correspond to a complete fibrous transformation of the nerve with loss of axons. We suggest a correlation between nerve lesions and the existence or absence of pain in the hip.

Adult↗

PubMed1986

Contiguous development of idiopathic osteonecrosis and osteoarthrosis in ischemia of a femoral head (radiological and morphological study).

In a 67 year-old man, an aseptic necrosis of the right hip joint developed side by side with an early oteoarthrosis characterized by an extensive narrowing of the upper interlinear space. The histological study revealed a diffuse ischemia which had evolved differently in the various regions of the femoral head. A well-limited necrosis appeared in a part of the weight-bearing zone, and osteoarthrosis developed in another one. In contrast with classical osteoarthrosis secondary to malformation, the osteoarthrotic lesions of the weight-bearing zone were caused by the ischemic angio-fibrosis of the bone marrow. At the beginning there was a resorption by the subjacent fibro-vascular tissue of the end-plate and of the deep layer of the cartilage. The osteosclerosis of this zone, in particular the eburnated plate, was formed mostly of fibre bone which rapidly became necrotic. Outside the weight-bearing zone, the subchondral angio-fibrosis and the non-inflammatory vascular pannus modified the articular surface.

Aged↗

PubMed1980

[Lesions of the nerves of the hip involving chronic rheumatic infections (ankylosing spondylitis, rheumatoid arthritis, arthrosis). Anatomopathologic study].

We have studied the nerves of the synovium and capsules of 6 hips with ankylosing spondylitis, 6 hips with rheumatoid arthritis and 14 cases of coxarthrosis either primary or secondary to a malformation. The nerves were studied with the usual methods of peripheral neuropathology. In the various diseases except 5 cases of coxarthrosis secondary to a malformation, the inflammatory and vascular involvements with tissue fibrosis were able to affect the nerves crossing the tissues. This nerve involvement could be the cause of articular pain. Despite the importance of the surrounding lesions, the nerves are preserved for a long time and this could explain the persistance of the pain.

Adult↗

PubMed1979

[Post surgical ossifications (total prosthesis) of the hips in subjects suffering from vertebral ankylosing hyperostosis].

In a series of 67 patients suffering from vertebral ankylosing hyperostosis (VAH) and who underwent surgery in one or both hips (93) with installing of a prosthesis, we observed in all the subjects post-surgical coxal ossifications, and in 57 of them, large or very large ossifications. These ossifications appeared solely during the first year following surgery, and their final volume was reached during this first year. The appearance of such post-surgical coxal ossifications during the VAH is for us a characteristic of the disease. This observation is a factor that points to a general and non local (vertebral) mechanism of the VAH.

Aged↗

PubMed1979

[Massive and sudden bone resorption in rapid destructive coxarthrosis. Radiologic and anatomic study].

Twenty hips with rapid destructive coxarthrosis (early form, 3; delayed form, 17) showed, during their development, a massive and sudden bone resorption. Preexisting problems of the bone structure of the hips were dispersed and constantly changing; they were different from those of common arthrosis and primary necrosis of the hip, conditions characterized by a progressive organization of the lesions in the relatively homogenous major areas. In five femoral heads sampled during the resorption, vascularization is ensured by a more or less dense network of capillaries. Medullar tissue was replaced by clumps of reticular cells, which later developed into differenciated cells (fibroblasts, osteoblasts and osteoclasts). The bone trabeculas also underwent several changes. Such tissue transformations are identical to those brought about by more or less severe experimental ischemia. In our samples, the confluence of centers of osteoclasia, very active, explains the massive bone resorption seen on x-rays.

Adult↗

PubMed1978

[The hip in vertebral hyperostosis].

The study of two series of cases affected by vertebral hyperostosis allows the authors to underline the frequency with which the hip joint is affected and to describe the destructive forms seen in hyperostosis of the hip. In a first series of 101 cases the authors picked up 145 pathological hips which were probably or surely associated with hyperostosis. These hip disorders presented in three types: Type I (already described by J. Forestier et al.) with peri-articular proliferation and radiological integrity of the joint space; Type II with hyperostotic proliferation and narrowing of the joint space; Type III with epiphysial destruction. The study of a second series "of the development of 58 cases of hyperostotic hip disease" followed for 2-16 years raises the consideration that these three types are in fact three stages in the evolution of the condition.

Hip↗

PubMed1978