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Biomedical subjects

F Jakobiec

Publications and source records attributed to F Jakobiec.

9 recordsLinked to original sources
PubMed1987

[A complication in gas surgery: injection of gas beneath the retina in a pseudophakic eye].

Report on an inadvertent injection of gas beneath the retina in a pseudophakic eye. The gas was injected through the pupil to tamponade a retinal break. Instead, however, it found its way under the retina, increasing the extent of the detachment. A thick, transparent membrane posterior to the intraocular lens prevented the gas from entering the vitreous space and diverted it laterally behind the iris to the ciliary body, where it penetrated between layers of the ciliary epithelium and entered the subretinal space. The gas became visible under the retina. The bullous redetachment had a mother-of-pearl-like opalescence characteristic of gas beneath the retina.

Aged↗
PubMed1986

Endophotocoagulation in vitrectomy with a carbon dioxide laser.

A continuous-wave carbon dioxide laser operating at a wavelength of 10.6 microns has been applied transvitreally by means of a miniature articulating arm and intraocular probe to produce chorioretinal lesions in albino white rabbit eyes. The advantages of using a carbon dioxide laser are its lack of pigment dependence, its ability to act both as a photocoagulator and as a phototransector, and its ability to deposit its energy in a well-defined area without adverse effect on neighboring ocular tissue. The main disadvantage of the carbon dioxide laser in vitreoretinal surgery is that in a fluid medium, such as the vitreous, the laser tip must be placed in direct physical contact with the target tissue to obtain a reaction.

Animals↗
PubMed1986

Morphological effects of gas compression on the cortical vitreous.

We used scanning electron microscopy to study vitreous in normal and perfluorocarbon gas-treated eyes of cynomolgus monkeys. The cortical vitreous of the normal (control) eye appeared to be a lamellar structure composed of sheets of collagen mesh. In the gas-treated eye there was shrinking and tearing of the lamellae. At six and 12 weeks after gas injection there was membrane formation at the edges of the torn lamellae.

Animals↗
PubMed1986

Gas vitrectomy in a primate model.

Total displacement of vitreous by an expanding bubble of a perfluorocarbon gas was studied in cynomolgus monkeys. The clinical observations and the gross dissection suggested that cortical vitreous might have been stripped from the retina; however, electron microscopy of frozen sections demonstrated that the collagen structure of the vitreous was compressed against the retina.

Animals↗
PubMed1986

The inadvertent injection of gas beneath the retina in a pseudophakic eye.

Gas injected through the pupil to tamponade a detached retina in a pseudophakic eye inadvertently made its way beneath the retina and augmented the detachment. A transparent membrane posterior to an iris-supported lens prevented the gas from entering the vitreous and diverted it laterally behind the iris, to the ciliary body, where is dissected between layers of ciliary epithelium and entered the subretinal space.

Aged↗
PubMed1985

Intraocular injection of lidocaine.

Lidocaine was inadvertently injected intraocularly in three patients. In the one patient who had not received prior mydriatics, the drug caused immediate dilation and paralysis of the pupil and diminished visual acuity to counting fingers. Retinal function began to improve after four hours and both retinal and pupillary function recovered completely by 16 hours. A second patient also recovered completely. The third patient developed a permanent field defect. The effects of intraocular lidocaine were then studied in an animal model. Lidocaine temporarily paralyzed the pupil in mydriasis and temporarily extinguished the b-wave of the electroretinogram. Light and electron microscopy study of the retina revealed no damage beyond that at the perforation site.

Animals↗
PubMed1984

Surgical management of malignant tumors of the lacrimal gland.

Malignant lacrimal gland tumors are rare but serious and life-threatening neoplasms. Patients frequently present with symptoms of less than 1 year duration, often demonstrating rapid change during the 6 months preceding diagnosis. Pain and periorbital sensory changes are also reported by patients. Radiographically, bone destruction is a strong indication of a lacrimal gland malignancy as is ophthalmoplegia. Radical three-dimensional resection utilizing a cranioorbital approach offers the best chance for total tumor removal. Immediate reconstruction with a scalp flap is essential for primary healing, as well as esthetic balance of the orbital region.

Adenocarcinoma↗