Preleukaemic abnormal myelopoiesis induced by chlorambucil: a case study.
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Biomedical subjects
Publications and source records attributed to F Jan.
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A prospective search for episodes of silent myocardial ischaemia (SMI) was carried out during sessions of haemodialysis in 62 patients with chronic renal failure and was positive in 37.1% of the cases. The occurrence of SMI is correlated with the number of cardiovascular risk factors (p = 0.008) and particularly with diabetes (p = 0.012), smoking (p = 0.007) and age (p = 0.02), as well as with the type of nephropathy that had caused the renal failure (p = 0.02). During a 6-month follow-up two patients died; both had silent myocardial ischaemia on Holter recordings. In these anaemic patients, haemodialysis might sensitize the detection of ischaemia by the concomitant occurrence of hypotensive, hypovolaemic or hypoxic episodes, thus playing a aggravating role. The existence of such episodes characterizes a subgroup of patients at high cardiovascular risk for whom the prognosis and the best therapeutic approach remain to be determined.
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Patients' right to information is strictly regulated by the French Code of Public Health that establishes the legal framework for delivering medical information. The Code of Medical Deontology also contains several articles concerning patients' rights, medical information, and medical secret. The patient's right to information must not be confounded with medical file property rights which is an ambiguous notion that has not yet acquired a perfectly acceptable legal definition satisfying all concerned. Currently, the physician, designated by the patient, is the only person legally authorized to deliver to that patient the desired information.
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