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Biomedical subjects

F Jeppesen

Publications and source records attributed to F Jeppesen.

At least 19 recordsLinked to original sources

[Prominent ears. Normal distance between the auricular edge and the side of the head].

The desire of the patients or their parents for surgical correction of protruding ears is not always in accord with the degree of deformity. As complications can not only ruin a good result but can make the situation worse, some degree of deformity must be present. In order to achieve some guidance in this evaluation we have measured the maximum distance between the side of the head and the helix border in 102 girls and 81 boys, aged 6-16 years. We found a range of ten to thirty-three. The mean value increased with age, and the distance in males was 2.89 mm greater than that found in females.

Adolescent↗

Respiratory tubes with nasal packings following septorhinoplasty.

The use of packings following septorhinoplasty is a matter of controversy. The recommendations go from gluing with fibrin glue only, if anything at all, over quilting stitches, perhaps in combination with silastic or teflon sheats or plates or these sheats alone, to the employment of various more substantial materials and in from 1 to even 14 days postoperatively. If long-term nasal packing is chosen following consideration of primary healing, patients will experience discomfort of mouth-breathing, but pressure in the ears, too. Therefore, our department has used respiratory tubes simultaneously with packings since 1971. In this study, 47 patients who underwent septo- and/or rhinoplasty were treated by nasal packings 6 days postoperatively. All patients were treated by silicone respiratory tubes, one group in all 6 days, one in 4 days only. Self-assessment as far as some typical complaints is concerned was carried out as well as tympanometry. There were statistically significant less complaints of pressure in the ears when tubes were used, and the period with tubes was significantly preferred to the period without. A low pressure in the middle ears was seen in many patients. The normalization was occurring significantly sooner with tubes. At the same time they seem to secure that the normalization will take place as fast as it has been demonstrated in an earlier study employing only 3 days of nasal packing. No synechias or perforations were seen at an early follow-up, 1-3 months postoperatively. When long-term packing is preferred, respiratory tubes then can be recommended as effective.

Adult↗

Anterior wedge excision in deflected nasal dorsum. A pilot study.

Correction of a deflected nasal dorsum and deviated septum is perhaps the most common problem in daily rhinosurgical practice. Up til now the basic principle of all surgical methods employed has been total mobilization. However, recurrences are seen. It is difficult to judge the importance of these results as no objective measurements are brought. In a new concept an anterior wedge is removed on the "long" side, leaving the rest of this side as support of the otherwise totally mobilized nose. In a pilot study of 36 patients the angle of deflection was measured on pre- and postoperative standardized photos. A median undercorrection of 1.5 degrees and 0.5 degree was obtained for the osseous and cartilaginous dorsum respectively, and the result was stable. The mean follow-up was 16.2 months (range 9-41 months).

Adult↗

Treatment of hay fever with sodium cromoglycate, hyposensitization, or a combination.

In 77 consecutive patients with grass pollen rhinitis as the only allergic disease, treatment with sodium cromoglycate (SCG) nasal spray, hyposensitization with aluminium hydroxide adsorbed extract of grass pollen as perennial treatment, and a combination of the two was compared. Specific serum-IgE, IgG and IgG4 were determined in patients who participated in three consecutive seasons. Significant immune response was found in the hyposensitization group, but not in the group treated with SCG. No correlation between the immunoglobulin responses and the individual symptom and/or medicine scores was found. Symptom and medicine scores were analysed in the 3 weeks with the highest pollen counts each year during 4 consecutive years. Higher scores were found in the group treated with sodium cromoglycate compared with the other two groups, but the difference was only significant for eye and total symptoms in the first season. None of the groups, however, suffered from more than mild to moderate symptoms even in the weeks with peak pollen counts. A significantly larger decrease in the wheals of the skin prick test was shown during hyposensitization than during treatment with SCG. No difference was found in the frequency of patients who became symptom-free or developed pollen asthma.

Clinical Trials as Topic↗

Curving effect of scarification or unilateral perichondrial lining on septal cartilage from human autopsy material.

From 20 cadavers septal cartilage was removed within 48 hours of death. From each cartilage four strips were prepared, two with preserved perichondrium on one surface and the other two not. On one strip from each group scarification was performed through about half the cartilage thickness. The curving of the cartilage strips was measured immediately after scarification and 5 h thereafter. The 17 mm. long strips showed a mean curving due to the scarification of 1.06 mm., 80 per cent of which occurred immediately after the scarification. It was demonstrated also that a unilaterally intact perichondrial lining per se entailed a curving averaging 0.52 mm., an effect which did not occur within the course of 5 h. Both effects were highly significant. It was not possible to demonstrate any correlation between these effects and donor age, cartilage thickness or orientation in the septum.

Adult↗