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Biomedical subjects

F Jurascheck

Publications and source records attributed to F Jurascheck.

At least 19 recordsLinked to original sources
PubMed1993

[Pharmacologic treatment of urinary dysfunctions].

After reviewing the nervous control of the lower urinary tract, the author defines the action of various drugs on the bladder, bladder neck, urethra (smooth and striated sphincter). The drugs are classified according to their stimulant or blocking effect on the sympathetic and parasympathetic nervous systems and alpha and betadrenergic receptors. Drugs acting on smooth and striated muscle fibres are then studied and the iatrogenic adverse effects of these drugs are mentioned.

Humans↗
PubMed1992

[Neurotransmission and the lower urinary system].

Various substances, called neurotransmitters, act as a chemical relay between the nervous and the tissue of the lower urinary tract. Some play also a role inside the muscle cell modulating the activity of the myofibrils. To allow a better pharmacochemical approach, these substances are described, their activity analyzed, with the purpose of helping specialists concerned by investigation or treatment of the lower urinary tract, to be able to act on their activity or change their pathologic abnormalities.

Humans↗
PubMed1991

[Neurophysiopathology of spinal lesions, evaluation of the 80s. Post-injury assessment and treatment of the neurogenic bladder in the acute period].

This introductory presentation deals with the recent pathophysiological aspects of the post-traumatic spinal cord lesion and the population concerned. The neurophysiology of the bladder and its sphincters is summarized so as to try and explain some disturbances occurring during the acute phase following a spinal cord injury; their clinical and urological aspects and the methods of bladder drainage.

Acute Disease↗
PubMed1988

[Neurotransmission and the lower urinary tract].

The neurotransmitter activity in the lower urinary tract is very complex. This paper reviews the main substances, known today, their agonists, antagonists, metabolic pathways and their action and discusses the site of action of neuropharmacological substances. The existence of a non-adrenergic, non-cholinergic pathway, in parallel with the sympathetic adrenergic and the parasympathetic cholinergic pathways is thus clearly admitted.

Animals↗
PubMed1987

Surgical treatment of the static perineal modifications in spinal cord or cauda equina lesions.

Severe dysuria, due to insufficiency of the perineal floor associated during micturition with a posterior tilting of the prostate-bladder block in lower or in associated upper and lower motor neuron lesions, can be treated surgically by a prostato cytso pexy. Since 1971, eight patients with post-traumatic conus and/or cauda equina lesions have been treated by this intervention. On the follow-up the satisfactory results appear to remain stable. An alternative surgical technique using the abdominal pyramidalis muscle is described so as to fix the prostate, associated with a bladder-pexy. The recurrence of dysuria, after the intervention, has always been caused by an additional lower urinary tract pathology. The comfort of the patients has been greatly improved.

Abdominal Muscles↗
PubMed1987

[The silent kidney. Evolving ultrasonic picture of emphysematous pyelonephritis: the vanishing kidney. Apropos of a case].

The authors report the progressive disappearing of the sonographical image of a previously visualized kidney in a case of emphysematous pyelonephritis. They have called the sonographic vanishing kidney "the sign of the Deaf Kidney". The non-visualisation of a kidney with advanced emphysematous pyelonephritis is due to the infiltration of the perirenal environment by a gas envelope and the filling of the excretory cavities by gas. The perirenal gas-bag forms a shield against ultrasonic waves. The sonographer must be aware of the eventuality of not being able to individualize a renal structure when wrapped in gas. He must then ask for a zonography of the renal area in order to confirm the gas-containing collection in the kidney.

Emphysema↗
PubMed1987

[Medical treatment of metastatic cancer of the kidney with a combination of vinblastine and recombinant interferon alpha IIa. Result of a phase I-II trial].

Usual treatments of metastatic renal cell carcinoma are not efficient. Phase II trials using Interferon alpha showed a low response rate (10 to 15%). We have conducted a phase I-II trial using a combination of Vinblastine and Recombinant alpha 2 A Interferon in 21 patients. The response rate is of 43% including 1 complete and 8 partial remissions, 5 stabilizations and 8 progressive diseases. In spite of important side effects, these results are promising.

Adult↗