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Biomedical subjects

F K Amroliwalla

Publications and source records attributed to F K Amroliwalla.

5 recordsLinked to original sources

Flying status and coronary revascularization procedures in military aviators.

This article proposes guidelines and recommendations for aeromedical disposal of military aviators after revascularization procedures for the treatment of stable obstructive coronary artery disease. A highly selected group of military aviators with a low risk of future cardiac events after successful angioplasty for single vessel disease or bypass surgery are reasonably safe for restricted flying duties. This is provided there is no past history of infarction, the aviators are free from subjective or objective evidence of myocardial ischemia on exercise electrocardiography (+/- stress thalium scan stress echocardiography), angiography shows no more than 30% lumen narrowing in major epicardial vessels and provided the ejection fraction is more than 50%. They should also be subjected to full annual cardiological reviews.

Angioplasty, Laser↗

Lipid lowering therapy and military aviators.

This article discusses the role of the newer lipid lowering agents (statins and fibrates) for the treatment of hyperlipidemias in military aviators. Special emphasis will be on long-term safety and the effects of these drugs on CNS functions pertinent to aviators. We propose that these new lipid lowering agents, such as hydrophilic statins and newer fibrates are reasonably safe in aviators with restricted flying duties, subject to long-term surveillance by a specialist.

Aerospace Medicine↗

Angiotensin converting enzyme (ACE) inhibitors in hypertensive aircrew.

Essential, uncomplicated hypertension is not uncommon in young or middle-aged aircrew. The choice of treatments available for its treatment was largely limited to diuretics and some accepted beta-adrenergic blockers. It is only 4 years since the choice was extended to the calcium-channel-blockers and the angiotensin converting enzyme (ACE) inhibitors, in civil aviation. In military aviation in the U.K., ACE inhibitors have been in use for less than 2 years. This paper surveys these choices and makes the case for the use of ACE-inhibitors, under controlled conditions. It also emphasizes that the functional studies, conducted to show the safety of ACE-inhibitors, were more comprehensive than for any of the predecessors. These methods of study should serve as models for the study of any drug in the future, before it is authorized for use in the aircrew.

Aerospace Medicine↗

Vaccination scar with soft-tissue atrophy restored by local insulin treatment.

A woman who had a deep scar on her left arm as a result of an influenza vaccination was treated with insulin. Monocomponent porcine insulin was injected into each quadrant of the pit. After 82 days' treatment her arm appeared normal and has remained so over seven months. Using insulin's ability to promote fat and protein synthesis is a simple and effective way of treating atrophied scars.

Adipose Tissue↗