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Biomedical subjects

F K Lynen

Publications and source records attributed to F K Lynen.

13 recordsLinked to original sources
PubMed1976

[Surgical treatment in premalignant lesions of the breast (author's transl)].

Established predisposition to developing of breast cancer is indicative of subcutaneous mastectomy. Subcutaneous mastectomy means a radical biopsy. Histological examination produces the best result by excluding a possible breast cancer in premalignant lesions. When a malignant tumour has been detected the operation can easily be extended to a more radical procedure (Halsted mastectomy). Subcutaneous mastectomy means a radical procedure of treating breast cancer--even with optimal cosmetic results. Early complications are rare, the late results are excellent.

Adult↗
PubMed1976

[Experimental studies of the effects of gastrin, neostigmine and prostaglandin on the motility of the trunculary vagotomized stomach].

The working effect of Gastrin, neostigmine and prostaglandin in regard to the emptying of the stomach was tested on 31 dogs that had undergone a truncular vagotomy. Gastrin and neostigmine were proved to increase the motility at the stomach pylorus but was not able to bring about a coordinated emptying pattern. Prostaglandin shows different effects on the emptying reflex of the stomach. PGF 2 alpha increases the motility on the measuring marks, but at different time intervals. Because of this a coordinated motility is made possible.

Animals↗
PubMedDate not supplied

Lesions after sphincterotomy.

Within the last years 70 transduodenal sphincterotomies at stringent indication have been carried out at the Department of Surgery of the RWTH Aachen. This means 9.2% of all operations caused by cholelithiasis. The lethality was 4.2%. The following postoperative complications where stated: a) the bleeding from the divided duct of sphincter with or without haemobile (1.4%), b) the post-sphincterotomy pancreatitis (9.5%) owing to lesion of the pancreatic duct, c) the retroperitoneal abscess with biliary peritonitis (1.8%), d) insufficiency of the duodenal wall or duodenal fistula (1.9%), e) postoperative disturbances of passage of the transsected sphincter Oddi. The haemorrhagic necrosing pancreatitis, the insufficiency of the duodenal wall, the retroperitoneal abscess and the bleeding postsphincterotomy force us to immediate re-operation, while functional disturbances like a spasm or an oedema are controllable pharmacologically and functionally for a short time.

Acute Disease↗
PubMedDate not supplied

Complications following cava catheterization.

The employment of cava catheterization in intensive care and emergency-treatment has dramatically increased. On the basis of our patients in the Surgical Clinics of the RWTH Aachen risks and complications of the central venous catheterization are explained. Six hundred and eighty-four cases have been examined--categorized according to the method of insertion and according to the technique. In a small randomized study, 60 cava catheters were individually examined bacteriologically.

Adult↗