Biomedical subjects
Publications and source records attributed to F K McVey.
Three cases of severe hypotension associated with the use of angiotensin-converting enzyme inhibitors (ACEIs) and intravenous administration of the synthetic colloid Gelofusin (Braun Medical Ltd) are presented. A possible mechanism of interaction between ACEIs and Gelofusin is discussed. All three patients were treated successfully.
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A case of refractory hypotension following propranolol overdose is reported. Management included isoprenaline, glucagon and extracorporeal circulatory support using femoral vein-femoral artery bypass. The unreliability of neurological observations, especially unreactive pupils, in the presence of drug overdose is reiterated.
A randomised double-blind trial was conducted to study the use of two commonly used premedication regimens and the subsequent incidence of sore throat. Fifty adult patients who underwent routine surgery were anaesthetised in a standard fashion after premedication with papaveretum and scopolamine or temazepam, and interviewed after operation to assess the presence of sore throat. A significantly higher incidence of sore throat was associated with the use of papaveretum and scopolamine.
Two hundred and forty-two routine surgical patients who had undergone general anaesthesia, were questioned about postoperative sore throat by one of two methods, either direct or indirect questioning. A significantly higher incidence of sore throat was obtained by direct questioning (p less than 0.001).