Biomedical subjects

F Kabukcuoglu

Publications and source records attributed to F Kabukcuoglu.

4 recordsLinked to original sources

PubMed2001

Mixed germ cell tumor of the ovary with sarcomatous component.

Germ cell tumors constitute a very complicated group of tumors of the ovary and their histogenesis is not yet clarified. Besides their histological heterogeneity, sarcomatous areas have also been described. A right ovarian mass was found in a 23-year-old female, who was being treated in the hospital for miscarriage. Disseminated omental metastases were detected during abdominal laparotomy. Pathological examination of the dissected material revealed the tumor to be a mixed germ cell tumor (immature teratoma and dysgerminoma) with sarcomatous component. Areas resembling granulosa cell tumor were also encountered. This ovarian tumor with many different histopathological features is presented with a review of the literature. The importance of thorough sampling in determining the type and extent of the malignant components is also emphasized due to their direct relation with the prognosis.

Adult↗

PubMed1999

Multiple diffuse fibrosarcoma of bone.

Multiple diffuse fibrosarcoma of bone is a very rare condition, with only 3 cases reported. Its presentation is like that of a multiple myeloma or a metastatic tumor, with multiple osteolytic lesions, and its extent is limited to the bones. Disseminated involvement of the vertebrae was detected in a 26-year-old man, suggesting a metastatic tumor; however, no primary organ or soft-tissue mass was identified. The histopathologic findings of the biopsy material were consistent with fibrosarcoma. Despite treatment, the patient died within 15 months.

Adult↗

PubMedDate not supplied

Long-term results of choledochoduodenostomy and T-tube drainage.

BACKGROUND/AIMS: In this study, gastric mucosal changes and the other clinical results of patients with choledochoduodenostomy (CDD) and T-tube drainage (TTD) were compared in a follow up period of at least 5 years. MATERIALS AND METHODS: The previous files of these patients were evaluated, physical examination and abdominal ultrasonography (US) and gastroscopic examination were made. Esophagus, stomach and the first two parts of the duodenum and size of the anastomosis in patients with choledochoduodenostomy were examined during gastroscopy. Two biopsies from antrum and corpus of the stomach were taken and sections stained with Hematoxylin and eosin for histopathological examination under light microscope. RESULTS: In total 45 patients, 21 of them with TTD and 24 of them with CDD, were accepted for the study. No difference was present between the mean age, female/male ratio, and interval between the operation date and endoscopic control of both groups (p > 0.05). Common bile duct was evidently wide in the CDD group at the first operation (p < 0.05). In the late postoperative clinical classification of the patients, moderate group was predominant, while incidence of alkaline reflux gastritis was obviously high in the CDD group (p < 0.05). No other difference in the results was present between the two groups (p > 0.05). CONCLUSION: According to our study long-term results of T-tube drainage is superior over choledo-choduodenostomy.

Adult↗

PubMedDate not supplied

The effect of H. pylori in perforation of duodenal ulcer.

BACKGROUND/AIMS: H. pylori has been described as an opportunistic pathogen attracted by changes in the gastric mucosa caused by inflammation and ulceration. However, the role of H. pylori infection in the perforation of duodenal ulcers has not yet been clearly determined. The aim of this study was to assess the prevalence of H. pylori infection in patients undergoing laparotomy for repair of a perforated duodenal ulcer. METHODOLOGY: Patients who underwent surgery for a perforated duodenal ulcer in our Surgical Unit between January 1994 and July 1996 were included in this study. The study population consisted of eighteen patients with a mean age of 32.7 (21-48) years. All of the patients were male. Patients with chronic duodenal ulcer perforation and with no contraindications for definitive surgery, such as peritonitis, shock (blood pressure <90 mm Hg), age >60 years, or more than a 12-hour elapse from the time of perforation, were treated by bilateral truncal vagotomy and Weinberg pyloroplasty. The ulcer was excised with the pyloric ring. The cut was then extented by about 2 cm on both the gastric and duodenal sides. Two biopsies were taken from the antral mucosa by endoscopic biopsy forceps. The defect was closed transversely. The ulcer specimen and the antral biopsies were fixed separately in 10% formalin solution and sent to the department of Histopathology. The specimens were stained with Hematoxylin-Eosin and examined for H. pylori . Sections of the ulcer specimen were especially investigated for the presence of H. pylori through all layers of the ulcer. RESULTS: H. pylori was found in the antral biopsies of 16 patients (88.8%). In seven of the ulcer specimens (38.8%), H. pylori was present in the mucosa and also extended through the wall of the ulcer. H. pylori was positive in the antral biopsies of all patients with H. pylori present in the ulcer wall. CONCLUSIONS: In our study, H. pylori was present at a high ratio in the antral biopsies of patients with duodenal ulcer perforation. The presence of H. pylori throughout the ulcer wall to a considerable extent emphasizes the fact that eradication of H. pylori is important in the treatment of perforated duodenal ulcer.

Adult↗