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Biomedical subjects

F Khoury

Publications and source records attributed to F Khoury.

At least 19 recordsLinked to original sources
PubMed2004

Surgery for aortic arch thrombosis.

A localized thrombus involving the ascending aorta and arch rarely occurs in the absence of an underlying etiology such as chest trauma, atherosclerosis, a hypercoagulable state or instrumentation. A review of the literature between 1966 - 2003 yielded 38 reported cases of localized aortic arch thrombi, 21 of which were treated by surgical excision of the thrombus using different approaches. In this communication, we describe this clinical entity, with its diagnosis and management. The technical details that are important to ensure the safe conduct of the procedure are discussed.

Aorta, Thoracic↗
PubMed2004

Familial antiphospholipid antibodies and acquired circulating anticoagulants.

Familial clustering of elevated antiphospholipid antibody levels has been described, but the reports are heterogeneous with regard to the characterization of the antiphospholipid syndrome (APS), coexisting autoimmune diseases and clinical implications. We report a familial occurrence of APS in two patients, in the presence of SLE in the mother and absence of autoimmune diseases in the daughter along with acquired circulating inhibitors in both cases: platelet inhibitor and factor IX inhibitor, respectively.

Adult↗
PubMed2001

Surgical therapy of peri-implant disease: a 3-year follow-up study of cases treated with 3 different techniques of bone regeneration.

BACKGROUND: Advanced peri-implant intrabony defects require comprehensive surgical treatment regimens different from periodontal therapy strategies. The purpose of this longitudinal trial was to evaluate the peri-implant outcomes following guided bone regeneration with 3 treatment protocols. METHODS: In 25 patients, 41 peri-implant defects with supporting bone loss >50% of the implant length were treated with flap surgery plus autogenous bone grafts alone (FG) (controls, n = 12) plus non-resorbable (FGM) (test 1, n = 20) or bioabsorbable barriers (FGRM) (test 2, n = 9) and supportive antimicrobial therapy. Following submerged healing, the membranes were removed (FGM), and the peri-implant probing depths (PD), probing bone levels (BL), mobility scores (PT), and intrabony defect height (DH) were radiographically evaluated at baseline, 6 months, and 1 and 3 years post-therapy. RESULTS: Non-surgical/anti-infective therapy resulted in a limited improvement of PD scores after 6 months. At the 3-year visit, surgical treatment revealed significant changes from baseline for the controls and both of the test groups for PD: 5.1 +/- 2.7 mm (FG), 5.4 +/- 3.0 mm (FGM), and 2.6 +/- 1.6 mm (FGRM), and for BL: 3.2 +/- 2.4 mm (FG), 3.4 +/- 2.4 mm (FGM), and 2.3 +/- 1.6 mm (FGRM), Mann-Whitney test, P < or = 0.05. The changes for DH and PT were significant only for FG- and FGM-treated subjects. The overall improvement for FGRM-treated patients during the 3-year observation was less marked. However, the differences between the 3 surgical treatment protocols did not affect the treatment outcomes after 3 years. CONCLUSIONS: Autogenous bone grafting is an appropriate treatment regimen to augment open crater-formed peri-implant defects. Although certain clinical situations require an additional fixation of barrier membranes, their routine application should be approached with caution.

Absorbable Implants↗
PubMed1999

Peri-implant conditions in periodontally compromised patients following maxillary sinus augmentation. A long-term post-therapy trial.

Augmentation of the maxillary sinus in the atrophied edentulous posterior maxilla is an integral part of implant prosthodontics. This study examined the clinical outcome in 50 periodontally compromised successfully treated subjects with severe maxillary atrophy following oral implantation with Brånemark, IMZ or Frialit-2 endosseous implants between 1991 and 1994. Simultaneous sinus augmentation was achieved using autogenous bone grafts harvested from the anterior mandible. Oral implants in 37 periodontally healthy patients directly placed in the stable local maxillary bone served as controls. The oral rehabilitation included implant supported restorations or removable superstructures over a period between 3 and 5 years. The peri-implant status of implant abutments inserted in the periodontal compromised augmented maxilla resulted in values comparable to the local maxillary bone except for the GCF rates with enhanced levels of 63.9 +/- 49.9 (controls 37.9 +/- 40.7). The average peri-implant Periotest values in the augmented maxillary sinus (test group) were -3.1 PT and +0.2 PT in the controls. The Periotest scores in the sinus area ranked between -7.0 and +5.0 with mean PT values of -1.5 for IMZ, -3.2 for Brånemark and -4.0 for Frialit-2 abutments. The functional integration of oral implants following sinus augmentation with autologous bone grafts and conventionally placed endosseous implants in the local bone was similar. The additional implant stabilization within the mandibular cortical bone grafts resulted in very low Periotest scores. In periodontally compromised subjects treated for chronic adult periodontitis with minimal maxillary bone height less than 5 mm the endosseous implantation with simultaneous sinus augmentation is recommended as an appropriate technique for long-term oral implant rehabilitation.

Adolescent↗
PubMed1991

Intra-oral keratoacanthoma: an eruptive variant and review of the literature.

Intra-oral keratoacanthoma, occurring in the absence of cutaneous lesions, is a rare lesion which may resemble a well-differentiated squamous cell carcinoma both clinically and histologically. A case is reported of two simultaneously occurring keratoacanthomas, of the eruptive variant, on the hard palate of a 25-year-old woman. A review of the English literature, which has identified ten documented cases to date, is presented.

Adult↗
PubMed1991

[Clinical comparative study of local anesthetics. Random double blind study with four commercial preparations].

In a randomized double blind study effects and tolerability of the local anesthetics Prilocaine 3% with Felypressin, Articaine 4% with Epinephrine 1/200,000 and 1/100,000, and Lidocaine 2% with Epinephrine 1/100,000 were tested. There was no significant difference between the four agents as far as effect on blood pressure, pulse, and tissue rehabilitation are concerned. Prilocaine can be used for extractions and surgical tooth removal. It can not be recommended for apicoectomy or implantation. The better results of Articaine 4% compared to Lidocaine 2% were statistically not significant.

Anesthetics, Local↗
PubMed1991

[General complications in dental local anesthesia].

In a prospective, randomised double blind study we recorded the rate of complications in dental anesthesia in more than 1500 patients using 4 commonly known anesthetic solutions. 228 of our patients (18.3%) noted headaches postoperatively. Furtheron we found syncopes, failures of anesthesia and nausea. Double vision was noticed once intraoperatively (Articain) and postoperatively (Lidocain). We found a high standard of security in dental local anaesthesia.

Adult↗
PubMed1989

[Filling cysts with type 1 bone collagen].

The good properties of bovine bone collagen type 1 for filling of bony defects was demonstrated in 56 cysts of the alveolar bone in 52 patients. 49 cysts (approx. 87%) healed without irritation. 8 months postop. complete reossification of the defects had been achieved in 20 (approx. 36%) of the cysts. Further 32 defects (approx. 57%) were markedly reduced. The discussion will compare the advantages of bone collagen and other materials.

Adolescent↗
PubMed1987

The bony lid approach for the apical root resection of lower molars.

The apical root resection of mandibular molars is an operation seldom performed and then one limited primarily to the lower first molars. Although the first paper on this topic was published at the beginning of the 20th century, little progress has been observed since then. This is due to the thickness of the buccal bony plate in the lower molar region which makes surgery very difficult and leads to a substantial loss of bone. The resultant limitation of the operating field prevents good vision. The aim of our approach is to minimize or to eliminate these problems by opening a bony lid above the roots which are to be resected. This can be made large enough for the surgeon to have easy access and good vision during apical surgery. At the end of the operation the same lid is replaced in order to avoid a bony defect and to facilitate the healing process. Of the 75 patients treated using this technique during a 3-year period, only one post-operative complication has been observed. A complete healing of the bone was observed in the majority of cases within 6 months.

Adult↗