Biomedical subjects
Publications and source records attributed to F Knudsen.
Thrombosis of the central veins as a complication of transvenous cardiac pacing fortunately is rare. A case is presented in which symptomatic thrombosis of the subclavian vein arose seven weeks after implantation of a new electrode. The frequency, pathogenesis, clinical picture, complications and treatment of the condition are briefly discussed.
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In a prospective study including 30 traumatized patients, levels of fibrinogen, fibrinopeptide A (FpA), fibrin monomers (FM) and fibrin degradation products (FbDP) were measured on admission and on days 1, 2, 3 and 7 after the incident. High levels of FpA, FM and FbDP were observed immediately after the trauma. Fibrinogen levels increased during the first 7 posttraumatic days whereas FpA and FM decreased. FbDP was significantly higher on day 7 than on day 3. All variables were to some extent correlated to the injury severity score. FbDP were significantly lower on the day after admission in 4 patients who developed pulmonary dysfunction compared with patients without this complication.
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