Radial keratotomy: improved predictability.
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Biomedical subjects
Publications and source records attributed to F Kremer.
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For contributing to the question of an existence of a diffusion of the unbound part of the fluorescein between choroid and retina in fluorescein angiography, on pigmented rats, after intravenous injection of Fluorescein sodium and Rhodamine B respectively, comparing observations were effectuated. Rhodamine B in its unbound form showed a distinct diffusion between choroid and retina and coloured all retinal layers in the late phases whereas in the case of the Fluorescein sodium, only a poor diffusion was observable. The similar spectral bands of the primary and secondary fluorescences render difficult the observation of the behaviour of the fluorescein dye.
The corneal neovascularization produced by NaOH burns was examined in two groups of pigmented rabbits following laser treatment. The treatment was carried out with energy level 500 mW, spot diameter 200 micron, and exposure time 1 s throughout. In the first group, a single newly formed vessel was coagulated in each case. Subsequent fluorescein angiography invariably showed an incomplete occlusion of the vessel. In the second group, we coagulated a section of the neovascularization network at its origin in the corneal limbus. After 48 h, fluorescein perfusion was once again observed, but the vessels were predominantly finer than before. Fluorescence microscopy revealed a rich neovascularization of the more superficial layers of the corneal stroma. To be successful, laser treatment must involve both supplying and draining vessels.
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