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Biomedical subjects

F Krispel

Publications and source records attributed to F Krispel.

9 recordsLinked to original sources

Technical note: an aid to radiation therapy simulation.

We have mounted a transmission liquid crystal display unit on the head of a radiotherapy simulator and projected, using the field light, a digitized fluoroscopic image with treatment prescription overlay. It is suggested that this approach (i) can aid visualization on the patient of complex field borders including those defined by multileaf collimators; (ii) could play a role in computed tomography or magnetic resonance based treatment planning and (iii) contributes to configuring non-coplanar beams.

Computer Simulation↗

Design of metallic electron beam cones for an intraoperative therapy linear accelerator.

A set of circular collimators and treatment cones from 5 to 12 cm diameter has been designed for an intraoperative accelerator (6-18 MeV) that has an optical docking system. Electron beam scattering theory has been used to minimize their weight while minimizing leakage radiation. Both acrylic and brass were evaluated as possible materials; however, because of substantial electron leakage through the lateral cone wall for acrylic, we have concluded that 2 mm thick brass walls are more desirable than acrylic walls. At 18 MeV, isodose measurements beneath the cones showed hot spots as great as 120% for both materials. The placement and dimension of an internal trimmer ring inside the brass cone was studied as a method for reducing the hot spots, and it was found this could only be accomplished at the expense of decreasing coverage of the 90% isodose surface. The effects of 1 degree cone misalignment on the dose distribution has been studied and found to generate changes of less than 5% in the dose and 3 mm in position of the 90% isodose surface. In a study of the contribution of the cone and its matching collimator assembly to x-ray room leakage, it was noted that although the treatment cone had a negligible contribution, the upper annuli of the upper collimator assembly contributed as much as 80% of the leakage at 16 MeV for the 5-cm cone.

Humans↗

[Irradiation of the para-aortic ducts. Presentation of an radiation technic with a largely fixed patient's position].

An irradiation planning program has been developed at the Radiologic University Hospital of Graz which allows an interactive optimization of the energy dose distribution of a Co-60 radiation. This program is running in a minicomputer of type DEC PDP-11/34 under the operation system RSX-11. With the aid of this system, a technique has been developed for irradiating the para-aortic lymph canals which complies with theoretical as well as practical optimization criteria. These optimization criteria are defined, and the usefulness of this irradiation technique is compared with a conventional method and demonstrated on the clinical example.

Aorta↗

[Comparison of different methods for the determination of the energy dose distribution of enclosed Cs-137 afterloading sources].

A low-dose afterloading unit of the type "Curitron" with Cs-137 sources is available at the Radiologic Hospital of the Karl-Franzens-Universität of Graz. The available sources are between 4.2 cm and 9.1 cm long. The corresponding activities of the individual sources are at present between 117 mCi and 383 mCi. The energy dose distributions around the sources were measured by means of an automatic dose measuring equipment and an additionally developed water phantom. Based on the measurement results, three rapid algorithms were developed and introduced as program modules into the existing therapy planning system which is running under RSX in a minicomputer of the type PDP 11/34. These algorithms are compared with regard to their precision and calculating speed, and the results are presented in form of energy dose distributions.

Brachytherapy↗

[Influence of the topographic situation of the uterus upon the irradiation planning in case of carcinoma of the cervix].

The authors demonstrated by means of computed tomography that some problems are offered by the standardized method of primary radiotherapy in case of carcinomas of the cervix. Especially when a low-dose curietherapy is applied without dose monitor, a radiation exposure of bladder and rectum exceeding the tolerance limit or a underdosage in the target volume are possible due to variable positions of the uterus and different thicknesses of the uterus wall, above all in the region of the cervix. The rate of complications can also be increased by a false, eccentric position of the intra-uterine applicator if the latter does not follow the cervical canal. In nearly half of 61 patients with carcinomas of the cervix of stage I or III according to FIGO, computed tomography scanning showed a false position of the intra-uterine applicator probe. Besides the correction of the probe position, the problem can be solved by a dose reduction and use of shorter applicators or by a modified relation between brachytherapy and percutaneous therapy.

Brachytherapy↗

[Studies about the dose distribution in the marginal field regions (author's transl)].

The authors have examined in an experimental study what influence is exerted by the width of the boundary line between two adjacent fields and by the dose inhomogeneity on the suture points lying in the region of the target volume. The results of this study are presented and the influence exerted on the dose distribution by different diaphragm sizes is shown by means of longitudinal and cross sections. The conclusion for the practical application of radiotherapy is that there exists a possibility to obtain homogenous dose distributions also beyond the borders of the field.

Cobalt Radioisotopes↗

[A pocket calculator programmed by magnetic cards as irradiation time table (author's transl)].

A representation of isodoses expressed as percentage of the possible dose maximum is the most practicable method to represent isodose schedules for the therapy planning. This implies, however, that an irradiation time table must exist for every irradiation unit which allows to determine the time of irradiation per irradiated field. A programme for the pocket calculator TI 59 is described which serves as irradiation time table.

Computers↗