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Biomedical subjects

F L Datz

Publications and source records attributed to F L Datz.

101 records · Page 6Linked to original sources
PubMed1982

Failure to detect extramedullary hematopoiesis during bone-marrow imaging with indium-111 or technetium-99m sulfur colloid.

A patient with postpolycythemic myeloid metaplasia developed an enlarging abdominal mass documented on TCT scanning. To distinguish between lymphoma and extramedullary hematopoiesis, marrow elements were imaged with indium-111 chloride and technetium-99m sulfur colloid. Because the mass failed to accumulate either tracer, a presumptive diagnosis of lymphoma was made and exploratory surgery was performed. The excised mass was found to consist of enlarged lymph nodes containing extramedullary hematopoiesis. Caution should be exercised in the use of In-111 or Tc-99m SC bone-marrow scans to diagnose sites of extramedullary hematopoiesis.

Bone Marrow↗
PubMed1981

Effect of wine on gastric emptying in humans.

The effect of wine on gastric emptying of meals was studied in 10 healthy male subjects. A dual radioisotopic method was employed utilizing isotope tracers added to the liquid (111In-diethyltriamine pentaacetic acid) and solid phases (99mT-tagged chicken liver) of the meal. In a random design subjects were fed two standardized 900-g meals containing 450 g of solid food ingredients and 450 g of either Cabernet Sauvignon (mean ethanol concentration = 9500 mg/dl) or low-alcohol Cabernet Sauvignon (mean ethanol concentration = 1312 mg/dl). In addition, 7 of the 10 subjects were fed wine and low-alcohol wine without solid food. Wine, when compared with low-alcohol wine, did not significantly alter gastric emptying of either liquid or solid food components.

Adult↗
PubMed1981

Effect of coronary blood flow and site of injection on Tc-99m PPi detection of early canine myocardial infarcts.

The effect of blood flow and site of injection on Tc-99m PPi uptake in acute myocardial infarction was studied in a group of 24 dogs. Temporary (3 hr) and permanent LAO occlusion models were used. Animals with the temporary occlusions showed scintigraphic visualization of the infarcts and reversal of the normal epito-endocardial Tc-99m PPi ratio in contrast to those with permanent coronary occlusions. The data demonstrate that early (within 3 hr) experimental canine myocardial infarcts can be detected with Tc-99m PPi if reflow to the area of infarction is provided. Delayed development of abnormal Tc-99m PPi scintigrams with acute infarction is related primarily to the initial lack of adequate blood flow to the damaged tissue, with subsequent development of adequate collateral flow allowing delivery and uptake of sufficient amount of the radiopharmaceutical for in vivo scintigraphic detection of the damaged area(s).

Animals↗
PubMed1980

Radionuclide evaluation of cardiac trauma.

Radionuclides were first used in the evaluation of myocardial trauma as a noninvasive means to detect hemopericardium. At present an important use is in the diagnosis of myocardial contusion, which can be difficult to recognize clinically, and often has nonspecific EKG and enzyme alterations. Technetium-99m pyrophosphate scintigraphy has been shown to be of significant value in confirming this diagnosis. Myocardial scintigrams are helpful in determining the degree of damage produced by penetrating wounds of the heart and can also detect electrical injury to the heart from accidental shock or cardioversion. In addition, multiple gated blood pool scans can determine the hemodynamic significance of mycardial trauma and evaluate for late sequelae such as aneurysm formation.

Contusions↗