Time-related adjustments in acid-base status of extracellular and intracellular fluid in chronic respiratory acidosis. SAM-TR-67-116.
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Acid-Base Equilibrium↗
Biomedical subjects
F L Scamman
Publications and source records attributed to F L Scamman.
An analysis of the factors leading to crossed gas lines causing profound hypercarbia during general anesthesia.
With increasing use of laparoscopic techniques to facilitate surgical procedures in closed cavities, our institution has installed piped-in carbon dioxide (CO2) in most of our operating rooms. This case report describes an occurrence of a nitrous oxide hose being connected to a CO2 outlet, resulting in profound hypercarbia. The factors, human and mechanical, leading to this error are discussed, as well as the process of diagnosis and the subsequent treatment.
Accidents, Occupational↗
Conscious sedation for procedures under local or topical anesthesia.
For many surgical procedures in otolaryngology general anesthesia is not required, but it is difficult to block completely all noxious sensations with local or topical anesthesia. Intravenously administered antianxiety and analgesic drugs can make the procedure more tolerable for the patient. A technique of conscious sedation based upon titrating diazepam to specific eye signs and fentanyl to specific end points is described. Safety is maintained by ensuring that the patient is always in verbal contact with the surgeon. The rationale for administering the sedative before the narcotic is presented along with the treatment of side effects and untoward responses to the drugs.
Administration, Topical↗
Supraglottic jet ventilation for laser surgery of the larynx in children.
To investigate the efficacy and safety of supraglottic jet ventilation for laser surgery on the larynx, ten studies were performed in seven children scheduled for laser excision of juvenile laryngeal papillomata. The children were anesthetized using halothane, nitrous oxide, fentanyl 3 micrograms/kg, and a succinylcholine infusion. After the Leonard-Jako laryngoscope was in place, jet ventilation with 70% nitrous oxide in oxygen was begun through a 12-gauge Medicut intravenous cannula inserted in the right-hand light channel of the laryngoscope. Tracheal, inspired, and end-tidal oxygen, nitrous oxide, nitrogen, and carbon dioxide were determined by mass spectrometry simultaneously with arterial blood gases. Oxygen and carbon dioxide levels were always within normal limits, the end-tidal to arterial differences averaging 50 +/- 9 and 2 +/- 1 (SEM) mm Hg, respectively. Room air entrainment averaged 32 +/- 2%. The end-tidal nitrous oxide averaged 39 +/- 2%. The advantages of this technique are that it leaves the larynx completely free for the surgeon and it eliminates the possibility of endotracheal tube ignition. Supraglottic jet ventilation for this surgical procedure was determined to be effective and relatively safe.
Anesthesia, Inhalation↗