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Biomedical subjects

F López Barea

Publications and source records attributed to F López Barea.

11 recordsLinked to original sources
PubMed1993

[Hepatic actinomycosis].

We present a case of primary liver actinomycosis in a patient who was operated on for a duodenal ulcus seven years before. A gastrectomy was performed. His gallbladder was also removed two years before. After the surgical treatment, followed by antibiotic and chemotherapeutic treatment, with the result of a pretended success, the patient developed a liver pyogenic abscess and portal hypertension. Authors emphasise the seriousness of the illness as well as its rarity even with an accurate treatment.

Actinomycosis↗
PubMed1991

Case report 694: Cervical paravertebral circumscribed myositis ossificans.

MO is a soft-tissue mass, reported only 3 times in the cervical paravertebral area in a search of the literature. We describe an additional case in a 10-year-old girl. We emphasize that in the unusual radial radiopaque roentgenographic image, a malignant tumor could be considered. We also stress that CT scanning can be of great value in establishing the diagnosis. The clinical types and the radiological and pathological features of MO are described in some detail and the "zonal" sign is described.

Cervical Vertebrae↗
PubMed1990

[Unusual bone tumor in a hemophiliac patient. Diagnosis using aspiration biopsy of the lesion].

Bone tumors due to repeated haemorrhages in haemophiliacs (haemophilic pseudotumours) usually are no diagnostic trouble. However, when x-ray findings are not conclusive, the differential diagnosis with malignant tumours may be difficult as bleeding complications hinder invasive diagnostic procedures. A fifteen year-old patient with severe haemophilia A is presented, who had a tumor in his left fibula with no previous traumatism. X-ray and CT scan images showed a broken cortical substance with reactive sclerosis and no alteration of the soft tissues. In order to establish the diagnosis and choose the adequate surgical management, aspiration with thin needle was performed through the cortical hole, under visual control with CT scan. A benign lesion was found upon study of the aspirate. No haemorrhagic or infectious complications developed after tumor dissection and filling with heterologous lyophilized bone. The final diagnosis was "giant cell reparative granuloma", an uncommon lesion in the fibula not previously reported in haemophiliacs. It was concluded that aspiration, when appropriately applied, may be a useful diagnostic procedure which should be borne in mind for the diagnosis of bone tumors in haemophiliacs.

Adolescent↗
PubMed1989

[Localized giant pseudopolyposis in Crohn disease].

A case is presented of Crohn's disease of prolonged evolution in a 32-year-old male, with clinical manifestations of intermittent obstruction due to localized giant pseudopolyposis in the colon. The bibliography is reviewed, anatomophathologic aspects are analyzed and the problems of differential diagnosis are remarked.

Adult↗
PubMed1986

Ewing's tumor in brothers. An unusual observation.

Ewing's sarcoma in two brothers is described. This has not been previously reported in the literature. Hypotheses which might explain this association are discussed. Genetic factors predisposing to the development of neoplasia are a very attractive possibility, although viral factors and chance association cannot be excluded.

Adolescent↗
PubMed1982

[Infantile hamartoma of the chest wall].

Although chest wall osseous tumors are frequent in infancy, a few cases have been reported in the last years. Most of these cases had a benign course although in many of them a malignant histological diagnosis was formerly made. We report a case of chest wall tumor in a two months old boy. The histological pattern was similar to that described by McLeod and Dahlin as "chest wall hamartoma of the infancy". Seven months after the tumor resection the child lived well and without recurrence.

Hamartoma↗
PubMed1979

[Hormonal multiplicity of an apudoma of the lung and pancreas. Characterization of the different peptides in the tumoral extracts (author's transl)].

The capacity which the cells of some tumors have of synthesizing, storing, and releasing hormonal polypetides constitutes the basic characteristic of the neoplasms of the APUD system. On many occasions these polypeptides are released as hormonal precursors of high molecular weight, with a minimal biological action in comparison with the real hormone (big ACTH, big gastrin, etc.), and they have no clinical expressivity. On other occasions they reproduce, however, the clinical syndrome of the hormone released in excess. The production of multiple hormones by a single tumor is not a common event. Here we present the case of a patient with an oat-cell carcinoma of the lung and a carcinoma of the pancreas, both histopathologically primitive. In this patient a syndrome of inadequate secretion of antidiuretic hormone was detected. By means of radioimmunoassay techniques, the existence of antidiuretic hormone, ACTH with a predominance of the components of high molecular weight (big ACTH and beta-LPH) and MSH was demonstrated in the tumoral extracts from the lung, pancreas, and from a mediastinal metastatic lymph node. While the concentrations of ACTH were much greater in the lung than in the pancreas, the opposite occurred for the antidiuretic hormone. The synthesis of MSH by the hypophyseal gland or by tumors is not at present recognized, but rather is considered as a degradation product during the process of extraction. The APUD system makes up the morphologic substrate of the syndromes of familiar multiple endocrine adenomatosis. The present case could represent a variant of sporadic multiple endocrine neoplasms which would have the same anatomical basis.

Adrenocorticotropic Hormone↗
PubMedDate not supplied

[Myocardial fibrosis in Shwachman's syndrome (author's transl)].

A case of a child affected by Shwachman's syndrome with a chronic diarrhea, cyclic neutropenia and bone defects is described. The child died at the age of eight months from an acute cardiac failure which showed analytical alterations compatible to an acute myocardial infarction. Pathologic study showed a pancreatic lipomatous hypoplasia, myocardial fibrosis and chondrometaphyseal dysplasia. Main hypothesis that relate pancreatic pathology and development of myocardial fibrosis are discussed, although there is a lack of definitive evidence for confirming such relation.

Bone Diseases, Developmental↗