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F Lappe

Publications and source records attributed to F Lappe.

2 recordsLinked to original sources

[Crystalluria in sows].

In 12 breeding sows the influence of high feed levels of calcium (Ca 16.0 mg/kg, P 5.9 mg/kg, Ca/P ratio 2.71:1), of a mineral feed mixture (Ca 13.8 mg/kg, P 8.3 mg/kg, Ca/P ratio 1,66:1) and of phosphorus (Ca 7.0 mg/kg, P 11.0 mg/kg, Ca/P ratio 0.64:1) on blood concentrations and renal excretion of minerals (Ca, P, Mg), electrolytes (Na, K) as well as development of urine concrements (crystalluria) was investigated in comparison to a control feed (Ca 7.3 mg/kg, P 6.0 mg/kg, Ca/P ratio 1.23:1). Besides the effect of water supply on formation of crystalluria was tested. Studies showed that especially high levels of phosphorus in the feed are responsible for excretion of urinary crystals. Sediment consisted of Ca phosphates mainly, which could be detected as amorphous crystals microscopically. Alkaline pH values in urine and an insufficient water supply supported development of crystalluria, but formation of crystals differed greatly between individuals. Cystoscopic investigations demonstrated inflammatory alterations of the bladder mucosa in sows with crystalluria. Therefore crystalluria in sows has to be considered as a risk factor for urinary tract infections.

Animal Feed↗

Electrodecantation of serum proteins.

The sedimentation of albumin under the action of the electric and gravitational fields was determined as a function of time in discontinuous experiments in a rectangular cell, using serum with the albumin fraction stained blue. It was shown that even under the influence of strong electric fields, the upper boundary of the albumin layer fell no further than the mid-point of the cell. In continuous single-stage separation of gamma-globulin from other serum proteins, only about half the gamma-globulins can be obtained from the solution because it remains homogeneously distributed throughout the solution and is only free from albumin and other proteins in the upper half of the cell. In experiments with continuously operated triangular cells, the process was optimized to give gamma-globulin of 97.5% purity in a yield of 80%, at serum flow-through rates of up to 0.5 l/h in a block composed of 40 cells.

Animals↗