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Biomedical subjects

F Luna

Publications and source records attributed to F Luna.

22 records · Page 2Linked to original sources

Mechanisms of natural selection in human rural populations, survey of a Mediterranean region (La Alpujarra, SE Spain).

Measures of fecundity and mortality among 476 women from a Mediterranean population in SE Spain (La Alpujarra) have been used to estimate the possibilities of the action of natural selection, using Crow's Index of Total Selection. The component due to differential fecundity was twice that attributed to mortality. The Crow's index variation in different populations seems to reflect a change in the action model of evolutionary factors from a primitive situation characterized by high mortality to a new situation typified by very low fecundity. The intermediate step could be represented by the rural communities defined by a sharp decrease of mortality while fecundity remains high. The selection potential found in La Alpujarra was in the range corresponding to these rural groups.

Adult↗

Digital dermatoglyphic patterns of Moroccan Arabs: relationships with Mediterranean populations.

Dermatoglyphic finger patterns and pattern intensity were examined in a sample of 204 (105 males and 99 females) adults from the authochthonous Arab population of south central Morocco. No significant sex differences were found for the overall finger pattern incidence or for the pattern intensity index. A high incidence of arches is the most remarkable characteristic of this population as compared to other Mediterranean groups. The significant differences from two previous sets of Moroccan data indicate a remarkable heterogeneity within the present day Moroccan population. Also important is the differentiation of this sample from other north African ethnic groups such as Berbers and Tuaregs. An analysis of the dermatoglyphic relationships using R-matrix analysis, shows a relative proximity between this Moroccan series and other southwest European groups as compared to north African populations.

Adolescent↗

Inbreeding incidence on biological fitness in an isolated mediterranean population: La Alta Alpujarra Oriental (southeastern Spain).

The incidence of parental inbreeding on biological fitness was analysed in a sample of the Alpujarrenian population. Fitness was estimated as the fertility and offspring viability from conception to reproductive age. The analysed sample represents about 45% of the population from the Alta Alpujarra Oriental in southeastern Spain, and includes 847 families and 2916 pregnancies. The results showed slightly higher reproduction in consanguineous marriages, but the differences observed were not statistically significant. Higher pregnancy numbers are usually interpreted as stemming from greater immunological compatibility of the mother and foetus and may also reflect the significantly higher early foetal viability in this population. According to other authors, the great number of births observed in Alpujarrenian consanguineous marriages is, in part, a reproductive compensation for increased perinatal and neonatal mortality found as a possible negative result of homozygous combinations of deleterious alleles.

Abortion, Spontaneous↗

[Iatrogenic trends as indicator of clinical competence in courses of specialization in medicine].

Iatrogenesis, understood here as an unfavourable effect to the health of patients provoked by the medical institution, has risen little interest in the researchers of the health area in spite of its growing presence. The present study had the aim of exploring the iatrogenic behavior of 659 recently graduated physicians by a questionnaire composed by clinical cases which described diagnostic and/or therapeutic situations that required the making of decisions. The questionnaire consisted of 600 general medical knowledge questions of which 112 explored commission of iatrogenic behavior. The group showed a iatrogenicity index of 39.5% ranging between 15.2% and 74.1%. When this iatrogenicity index was compared to that of global medical knowledge (600 questions) no correlation was found. It is concluded that the "iatrogenicity" index of this group is high and lacks correlation with the global medical knowledge. This suggests that the individualized and careful use of the diagnostic and therapeutic resources suitable for specific situations in patients does not receive sufficient emphasis during the teaching-learning process nor does it play a prominent role within the priorities of knowledge that are learned in the school of medicine. The need to deepen our understanding of the iatrogenic behavior of the physicians at different levels of their professional training is emphasized.

Clinical Competence↗