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Biomedical subjects

F M Beck

Publications and source records attributed to F M Beck.

At least 73 records · Page 4Linked to original sources
PubMed1985

Inhibition of root surface caries in rice rats: use of a sodium fluoride dentifrice.

A sodium fluoride-containing dentifrice (Gleem) was evaluated for its efficacy to inhibit root surface caries in the rice rat. The dentifrice was diluted 50/50 with water so that the slurry contained 500 ppm fluoride. This slurry, a solution of 5000 ppm fluoride, and demineralized water were applied to the molar teeth twice daily for 10 weeks. Another group of rats was given 50 ppm fluoride in the drinking water. There was significantly less root surface caries in all groups of rats which received fluoride than in the demineralized water control animals. However, none of the fluoride preparations inhibited the loss of alveolar bone.

Alveolar Process↗
PubMed1985

Effect of anti-oxidants on growth and lactic acid production by Streptococcus mutans.

The effects of three anti-oxidants--tertiary butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT)--on both growth and lactic acid production by eight cariogenic strains of Streptococcus mutans were investigated. Synergistic inhibitory effects of potassium sorbate on lactic acid production were also determined. All three anti-oxidants are phenolic derivatives and are commonly used in food systems due to their excellent "carry-through" properties during processing. Growth inhibition was determined by turbidity measurements at 600 nm. Lactic acid was assayed by gas chromatography, and bacterial DNA was assayed by the diphenylamine reaction. There were reduced growth levels of S. mutans due to the anti-oxidants and potassium sorbate for at least 12 hr, with TBHQ and BHA still inhibiting growth at 24 hr. Nearly all concentrations of anti-oxidants and potassium sorbate reduced lactic acid production by S. mutans, but only TBHQ significantly inhibited lactic acid production when the amount of acid per microgram DNA was calculated. A synergistic reduction of lactic acid production by S. mutans does occur in most combinations of potassium sorbate with anti-oxidants.

Anisoles↗
PubMed1984

Anticariogenic effects of tea in rats.

Teas varying in fluoride and tannin concentration were evaluated in rats for anticariogenic activity. There was a direct correlation between fluoride in tea and the inhibition of sulcal caries in rats, whereas no relationship was observed between tannin and this type of lesion. Teas also had a significant effect on caries progression and imparted a black stain to the teeth.

Animals↗
PubMed1984

Effect of cheese, with and without sucrose, on dental caries and recovery of Streptococcus mutans in rats.

The objective of this study was to determine the effect of aged and young cheddar cheese with and without added sucrose on dental caries and the associated recovery of implanted Streptococcus mutans. Very little caries was observed in rats consuming cheese without sucrose. There was an increase in caries in rats fed cheeses with 20% sucrose, but this increase was not significant. There was significantly greater caries activity in rats fed standard diets containing 20% or 5% sucrose (SLS or MIT 305) than in rats fed cheeses containing 20% sucrose. Rats fed cheese or powdered diets containing sucrose had significantly higher frequency of recovery and higher levels of S. mutans infection than did rats fed cheese containing no sucrose. This study confirms the low cariogenic potential and possible cariostatic activity of cheddar cheese in rats. Since cheddar cheese with sucrose did not significantly interfere with S. mutans implantation, the cariostatic mechanism is apparently unrelated to a direct antimicrobial effect on S. mutans.

Animals↗
PubMed1984

The effects of various levels of ascorbic acid intake upon growth and organ weights of guinea pigs.

The purpose of this study was to evaluate the systemic effects of varying levels of orally administered ascorbic acid during wound healing in guinea pig oral mucosa. Forty five Murphy/Hartley guinea pigs were randomly placed into four groups and fed an ascorbic acid deficient diet for 2 weeks. Each group of animals then received a daily oral supplement of the following doses of ascorbic acid: 0.5 mg, 5.0 mg, 50 mg, and 250 mg. All animals were weighed twice a week. Twenty eight days later, a standardized wound was made in the premaxilla. On day 35, all animals were sacrificed. Blood samples were evaluated for levels of ascorbic acid. Thirty nine samples showed insignificant levels of vitamin C, 32 of which showed no ascorbic acid. Organ to body weight ratios were calculated and compared. Spleen to body weight ratios were not affected by different ascorbic acid levels. High levels of ascorbic acid caused a significant increase in adrenal gland to body weight ratios. Varying the levels of ascorbic acid did not affect growth prior to surgical wounding. Increased levels of ascorbic acid enhanced body weight recovery post surgically.

Adrenal Glands↗
PubMed1983

Strain-related differences in pathogenicity of Candida albicans for oral mucosa.

Fifty female Sprague-Dawley rats were divided into five groups of 10 animals and were given a low concentration (0.01%) of tetracycline in drinking water. Four of the groups were orally inoculated weekly with the yeast Candida albicans for a period of 25 weeks. Each group received a different strain. Three of the four strains of yeast were consistently recovered upon culture of the oral cavity during the course of the study. Two of the strains produced grossly visible lesions (four of 10 and two of 10 animals) on the midline dorsal tongue, whereas no lesions were seen in the other two experimental groups or the control group. Clinical findings were supported histologically. These data suggest definite strain-related differences in mucosal pathogenicity for the lingual mucosa of rats among the strains of C. albicans studied.

Animals↗
PubMed1981

Blood pressure and heart rate responses to anticipated high-stress dental treatment.

Twenty-four healthy adults participated in a study to determine the effects of anticipated high-stress dental treatment on blood pressure and heart rate. Blood pressure, heart rate, and state anxiety were assessed prior to four consecutive dental appointments. Appointments 1, 2, and 4 were of relatively low stress and appointment 3 was of relatively high stress. Blood pressure was unaffected while heart rate was highest prior to appointment 3 and lowest prior to appointment 1.

Adolescent↗
PubMed1979

Recognition and management of the depressed dental patient.

Depressive illness may affect the patient's response to dental care. It has been implicated both as a causal factor and a sequela in facial pain syndromes. Depression is treated with various medications that may influence function and health of the oral cavity and that may adversely interact with drugs used to control pain and anxiety.

Antidepressive Agents, Tricyclic↗